Drugs & Genetics: Why Do Some People Respond to Drugs Differ
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- Project Question: My science project focuses on using an online database to see how genetic mutations affects why people react to drugs differently.
- Project Due Date: April 19, 2013
- Project Status: I am conducting my research
Drugs & Genetics: Why Do Some People Respond to Drugs Differ
What are the independent and dependent variables and control for this experiment? We are using an online database to determine why people have different reactions to prescription drugs and how this is affected by genetic mutations.
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Hi,
I am sorry for the delay answering your question. I asked another expert to come help with this one - I am not quite sure about database questions. Tonya
I am sorry for the delay answering your question. I asked another expert to come help with this one - I am not quite sure about database questions. Tonya
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- Joined: Wed Apr 10, 2013 4:36 pm
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- Project Question: My science project focuses on using an online database to see how genetic mutations affects why people react to drugs differently.
- Project Due Date: April 19, 2013
- Project Status: I am conducting my research
Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Here is the link to my project if that helps: https://www.sciencebuddies.org/science- ... p006.shtml
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Hello,
Since your project is really a research project and you aren't doing an experiment yourself...these terms don't really apply.
If you look at testing the same drug on a variety of people to see how they react based on their genetcis, the independent variables would be the people themselves, and the drug you are giving them. Basically any input into the experiment that has an impact on the result. The people could have many variables themselves such as age, sex, ethnicity and genetic make up that could all impact the result of the experiment, being is the drug effective. The dependent variable would be whether or not the drug is effective....this result could potentially be impacted by any of the independent variables. Does this make sense?
Since your project is really a research project and you aren't doing an experiment yourself...these terms don't really apply.
If you look at testing the same drug on a variety of people to see how they react based on their genetcis, the independent variables would be the people themselves, and the drug you are giving them. Basically any input into the experiment that has an impact on the result. The people could have many variables themselves such as age, sex, ethnicity and genetic make up that could all impact the result of the experiment, being is the drug effective. The dependent variable would be whether or not the drug is effective....this result could potentially be impacted by any of the independent variables. Does this make sense?
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Hello,
Is there a control for this project?
-Arnlan
Is there a control for this project?
-Arnlan
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Best,
-Arnlan
Best,
-Arnlan
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Hi Arnlan,
I have to agree with the previous expert, that since this is really more of a research project than an experiment you are doing, the variables, controls, etc. don't entirely apply. However, following what KatieC said, imagine if you personally were doing an experiment to test whether a drug affected people with a specific genetic mutation differently from people without the mutation. Can you try to figure out what your control group would be?
In order to explore whether the drug affects people with this mutation differently, you couldn't just test the drug on those people. You would need to also include a group of people without the mutation to serve as your controls, so you'd know how "regular" people respond to the drug. Like KatieC said, in an experiment set up this way, the independent variable (what you control) would be the presence of absence of a specific genetic mutation in people, and your dependent variable is the effectiveness of the drug. To confirm that the effectiveness of the drug is dependent purely on the genetic mutation, you would also want to control other possible variables between the groups (i.e. sex, age, ethnicity) and these would become controlled variables.
I hope this makes sense. Please post again if you still have questions about these concepts.
JMP
I have to agree with the previous expert, that since this is really more of a research project than an experiment you are doing, the variables, controls, etc. don't entirely apply. However, following what KatieC said, imagine if you personally were doing an experiment to test whether a drug affected people with a specific genetic mutation differently from people without the mutation. Can you try to figure out what your control group would be?
In order to explore whether the drug affects people with this mutation differently, you couldn't just test the drug on those people. You would need to also include a group of people without the mutation to serve as your controls, so you'd know how "regular" people respond to the drug. Like KatieC said, in an experiment set up this way, the independent variable (what you control) would be the presence of absence of a specific genetic mutation in people, and your dependent variable is the effectiveness of the drug. To confirm that the effectiveness of the drug is dependent purely on the genetic mutation, you would also want to control other possible variables between the groups (i.e. sex, age, ethnicity) and these would become controlled variables.
I hope this makes sense. Please post again if you still have questions about these concepts.
JMP
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Thank You So much
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Best,
-Arnlan
Best,
-Arnlan
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- Project Question: Science Project: To show that genetic mutations within individuals lead to changes in the transcription of amino acid sequences and that this accounts for unexpected reactions to commonly prescribed medications.
- Project Due Date: Due 12/18/13 - I apologize for the short timeline. Unfortunately, we were not given the adequate 3 months suggested by your website and instead have had to accomplish our goals within a week.
- Project Status: I am finished with my experiment and analyzing the data
Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
Dependent variable: The individual’s response to a prescribed medication
Independent variable: Genetic mutations in isolated individuals
Control: The general population and the standard response expected
Hope this helps,
Quinn.
Independent variable: Genetic mutations in isolated individuals
Control: The general population and the standard response expected
Hope this helps,
Quinn.
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
So using these variables you provided with me, it is used on the website on the procedures?
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Best,
-Arnlan
Best,
-Arnlan
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- Posts: 80
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Di
I don't know how test it using the phamgkb, i have done the experiment following the procedures already. I don't really know how to spice up the project. Can you also help me figure out how to write the hypothesis? How do you use people in this project using the website. I need help asap!!JMP wrote:Hi Arnlan,
I have to agree with the previous expert, that since this is really more of a research project than an experiment you are doing, the variables, controls, etc. don't entirely apply. However, following what KatieC said, imagine if you personally were doing an experiment to test whether a drug affected people with a specific genetic mutation differently from people without the mutation. Can you try to figure out what your control group would be?
JMP
Thank You,
Arnlan
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Best,
-Arnlan
Best,
-Arnlan
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Re: Drugs & Genetics: Why Do Some People Respond to Drugs Differ
For the experiment. I know it's a research project but what kind of graphs or data tables would you make? Like I know what to do for the experiment but it's so confusing. I am researching the drug clopidogrel (as it says on the procedures) but what do you do once you grab the info. How would you make the conclusion? This project is a lot harder than I thought and I am slowly starting to regret picking it for my science fair lol. But the part I'm really confused of is just how to reach the conclusion and how to make the data tables and what type of graphs I could make. Please help I only have 2 weeks left so some advice would really help