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by Diane35 » Fri Jan 04, 2013 4:21 am
Hello,
I am doing a project on SSRI and serotonin syndrome, and I would like to make a chromatography of Prozac, in order to bring out the presence of Fluoxetine.
I would like to know what solvant I should use, and what equipment I need, because I could'nt find anybody able to answer me yet...
Thank you for taking the time to read this, and sorry if I made some language mistakes, English is not my native language
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Diane35
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- Posts: 1
- Joined: Fri Jan 04, 2013 3:58 am
- Occupation: Student : 11th grade
- Project Question: SSRI and Serotonin Syndrome
- Project Due Date: February 1st, 2013
- Project Status: I am conducting my experiment
by donnahardy2 » Sun Jan 06, 2013 11:51 am
Hi Diane,
Welcome to Science Buddies! Your English is very good and I think I do understand your question.
This is a great topic for a science project. You should try doing a search for "analysis of fluoxetine" and its metabolite, norfluoxetine. This should bring up lots of references for you.
For example, here is a reference that describes a chromatography method for this type of analysis. Do you have access to a research laboratory with HPLC equipment? The analysis requires a specialized chiral column and the chromatography conditions are described in the abstract.
http://www.ncbi.nlm.nih.gov/pubmed/21752386Please post again in this topic if you need more information.
Donna Hardy
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donnahardy2
- Expert
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- Joined: Mon Nov 14, 2005 12:45 pm
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