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Science Fair Project Idea
How a biological system functions is a consequence of the 3-D structures of biological macromolecules like proteins and protein complexes. Proteins can be categorized into different protein families based upon sequence, structure, and function. Typically, proteins in the same family have similar biochemical functions. You can investigate the structure of a protein by using protein databases (Entrez Protein, SwissProt, PDB) and 3-D computational models. You can compare the structures of… Read more
BioChem_p021
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
BioMed_p009
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Time Required Short (2-5 days)
Prerequisites Basic understanding of how genes are turned into proteins.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Did you ever wonder about your ancient ancestors? Who they were? Where they came from? In this science project, you will investigate the secrets of your distant past as revealed by your DNA. In order to obtain a sample for DNA analysis, you will scrape a soft swab inside your mouth to collect cheek cells. The cheek cell sample will be sent to a lab for processing, and the results of the analysis will be sent to you. Based on the genetic markers in your DNA, the ancient clan that your… Read more
Genom_p014
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Time Required Very Long (1+ months)
Prerequisites You should be familiar with the concepts of basic human genetics.
Material Availability Readily available
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
The Sun is the ultimate source of the energy that powers weather systems on Earth. Geomagnetic storms are sun-powered storms in the upper atmosphere, arising from energized particles that are periodically ejected by the Sun. Among other effects, geomagnetic storms can wreak havoc with earth-orbiting satellites, and disrupt satellite communications. The global positioning system (GPS) is a network of 24 earth-orbiting satellites that constantly sends radio signals through the earth's… Read more
Weather_p009
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Time Required Very Long (1+ months)
Prerequisites You will need access to a WAAS-capable GPS receiver for this project. You will need to understand how to operate the GPS receiver. Note that WAAS signals are only available in North America.
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD () to submit your sequence for an analysis of its predicted 3-D structures based upon thermodynamics… Read more
BioChem_p023
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Here is a challenging problem for anyone with an interest in geometry. This project requires background research to solve it, but it is an excellent illustration of visual thinking in mathematics. Figure 1 below shows a series of circles (iC₁, iC₂, iC₃, ..., iC₃₀), inscribed inside an arbelos. What is an arbelos? The arbelos is the white region in the figure, bounded by three semicircles. The diameters of the three semicircles are all on the same line segment, AC,… Read more
Math_p011
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Time Required Average (6-10 days)
Prerequisites Good grasp of Euclidean geometry, a firm understanding of how to construct a mathematical proof, determination
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more
Genom_p002
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Time Required Long (2-4 weeks)
Prerequisites High School Biology, excellent computer skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail The human kidney is the most commonly transplanted organ in the United States, numbering more than 17,000 transplants in 2010 alone! But kidney transplantation technology faces a lot of challenges, including a shortage of kidney donors and the need for recipients to take immunosuppressant drugs to keep their bodies from rejecting a transplanted kidney. In this science project, with the help of bioinformatics databases, you will explore how a kidney could be bioengineered using stem cells,… Read more
BioMed_p013
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Time Required Short (2-5 days)
Prerequisites An advanced biology course or equivalent understanding of how cells respond to environmental stimmuli and signaling pathways.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail When is an animal considered endangered? When will it become extinct? What happens when a population has reached the limits of its resources? What happens to a population when a habitat changes? These are some of the questions population biologists try to answer. They use population models, created from math equations, to predict what will happen to a population over time. If you want to see how modeling is done and make some predictions of your own, you certainly won't need a crystal… Read more
EnvSci_p049
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Time Required Average (6-10 days)
Prerequisites Only arithmetic is needed to make the model; however, some exposure to simple programming will make this science fair project easier, and exposure to the Euler number, e, will make the model more understandable.
Material Availability Readily available
Cost Average ($50 - $100)
Safety No issues
Science Fair Project Idea
thumbnail You have probably had X-rays taken at the dentist's or doctor's office, but do you know how the X-ray images are made? Images made using X-rays, also called radiographs, are considered to be relatively safe to take, even though they are made using a small amount of radiation, specifically electromagnetic radiation. Radiation is energy that travels through space as either waves or high speed particles. Watch this video to learn more about electromagnetic radiation. Watch… Read more
HumBio_p034
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Time Required Long (2-4 weeks)
Prerequisites Basic understanding of radiation and making pictures using film.
Material Availability See How to Build an X-ray Machine for a detailed list of materials that will need to be ordered.
Cost Very High (over $150)
Safety See Introduction to Radiation and Radiation Safety for safety information.
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