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Science Fair Project Idea
thumbnail Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change the sequence of the DNA. Will the same enzymes still cut the new DNA sequence? Read more
BioChem_p014
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Native plants are important for both ecological and medicinal reasons. However, most native plants are not very well studied. One way to know more about these plants is to understand which other species of plants they are most closely related to. In this science project you will sequence part of the chloroplast genome from a native plant and use this information to determine its evolutionary relationship to other species of plants. If the plant you chose has not been sequenced before, you can… Read more
Genom_p012
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Time Required Long (2-4 weeks)
Prerequisites High school biology class; familiarity with using the PCR machine and gel electrophoresis equipment, and/or using the equipment with a mentor.
Material Availability You will need specialized pieces of equipment, including a PCR machine (thermocycler) and a gel electrophoresis apparatus. If your school does not have this equipment you might want to seek out a mentor at a junior college, university, or biotechnology company. If you have the resources you can do the DNA sequencing yourself, otherwise you can send the samples to Dr. Baysdorfer at California State University, East Bay, see Experimental Procedure for more details.
Cost High ($100 - $150)
Safety This project uses ethidium bromide, which is a carcinogen. Always wear gloves and safety goggles when handling. Dispose of the ethidium bromide according to your school or institute's hazardous waste protocols. If you have concerns, ask your teacher or mentor for advice.
Science Fair Project Idea
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use a Web-based… Read more
Genom_p004
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Time Required Very Short (≤ 1 day)
Prerequisites You should have studied Life Science or Biology and also need good website navigation skills.
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Did you ever wonder about your ancient ancestors? Who they were? Where they came from? In this science project, you will investigate the secrets of your distant past as revealed by your DNA. In order to obtain a sample for DNA analysis, you will scrape a soft swab inside your mouth to collect cheek cells. The cheek cell sample will be sent to a lab for processing, and the results of the analysis will be sent to you. Based on the genetic markers in your DNA, the ancient clan that your… Read more
Genom_p014
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Time Required Very Long (1+ months)
Prerequisites You should be familiar with the concepts of basic human genetics.
Material Availability Readily available
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
This is a project about the "molecular alphabet" of DNA. With just four "letters," it manages to keep track of the plan for an entire person, and keep a complete copy in nearly every cell. This project will help you start learning this new alphabet. Read more
Genom_p005
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Time Required Very Short (≤ 1 day)
Prerequisites You should have studied Life Science
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Do you know how to find the north and the south poles of a magnet? What materials are more magnetic than others? Is there a way to measure how strong a magnet is? Is there a way to measure the strength of an electromagnet? How much does the material that is in the core of the electromagnet affect its magnetic strength? With this project, you'll be able to answer these questions and many others. You will learn how to build and use a simple meter for measuring magnetic field intensity. Read more
Elec_p030
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Specialty items are needed. See the Materials tab for details.
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more
Genom_p002
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Time Required Long (2-4 weeks)
Prerequisites High School Biology, excellent computer skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Find out the real explanation for why your parents are so weird! Here is a project that lets you explore "the net" to find out why your "DNA blueprint" is so important to health and disease. In this project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Following a simple black line seems pretty easy, right? But think about it; how do you know what is the line and what is not the line? What if you wanted a robot to follow that line? How would it know what you wanted it to follow? Robots can use simple techniques to sense their surroundings and change their behavior based on what they see. In this engineering project, you will build your own robot that will follow a path without using complicated electronics or programming. Read more
Robotics_p021
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Time Required Average (6-10 days)
Prerequisites You should be familiar with, or be willing to learn how to wire circuits on a breadboard. A little soldering is necessary to complete this science project, so you should also be familiar with the procedure or be able to find a helpful friend or adult.
Material Availability Readily available. See the Materials and Equipment list for details.
Cost Average ($40 - $80)
Safety If you are using the coping saw to make the wheels, use caution and be sure to wear safety goggles. Some steps require soldering, which involves very high temperatures. Use caution when soldering and when using other building tools. An optional step involves a product that must used in an open area, following the manufacturer's directions.
Science Fair Project Idea
thumbnail From 2005 to 2008, 48% of everyone in the U.S. was using at least one prescription drug, and 21% of people were taking three or more drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic mutations associated with a different response to a drug? In this science project, you will explore an online drug and genetics database to… Read more
BioMed_p006
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
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