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Others Like “Protein Structure and Function”

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Science Fair Project Idea
Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD () to submit your sequence for an analysis of its predicted 3-D structures based upon thermodynamics… Read more
BioChem_p023
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Some proteins are soluble in aqueous solutions and some are not. Insoluble proteins can be a problem because the proteins can form large aggregates in solution which are difficult to purify, crystallize, and use in experiments. Compare the amino acid sequence and 3-D structures of some soluble and insoluble proteins (Berman, 2000). Is the structure polar or non-polar, and how might this affect solubility? How do detergents make an insoluble protein more soluble? Investigate how this… Read more
BioChem_p018
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Time Required Long (2-4 weeks)
Prerequisites Basic introduction to chemistry
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Minerals are sometimes precious, like diamonds. But most minerals are very common, like sodium, which is found in salt. How are minerals found and identified? How are our mineral resources distributed? Visit the USGS Mineral Resource Program to find mineral resources in your state. How are satellite images used to identify potential mineral sources? You can also find out how minerals are identified using spectroscopy. How are potentially harmful minerals, like mercury, dealt with? Visit the… Read more
Geo_p026
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Time Required Average (6-10 days)
Science Fair Project Idea
Can you imagine Valentine's Day or Halloween without chocolate? Well, if you're a chocolate lover brace yourself for the bad news. According to the United States Department of Agriculture (USDA), "Worldwide demand for cacao now exceeds production." If there isn't enough cacao, the major raw ingredient for chocolate, then the chocolate supply will dwindle. Hang on! Before you start rushing to the store to buy all the chocolate you can get your hands on, a solution is already in the works. In… Read more
Genom_p021
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Time Required Long (2-4 weeks)
Prerequisites A high school level introductory biology course is a prerequisite for this science project.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The different species of wood used in construction offer a variety of challenges based on density, porosity, oils in the wood, flexibility, elasticity, etc. The intended use, e.g., structural or cosmetic, presents different challenges as well. The glue must be compatible with the wood, the use, and the climate, so many experiments are possible. For example, you could design an experiment to test the durability of different adhesives using the same wood. Or, you could try different wood… Read more
MatlSci_p027
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Time Required Very Long (1+ months)
Science Fair Project Idea
Our forests are a very important natural resource that need to be managed wisely. We use wood products for many different purposes: building materials, paper, cardboard, furniture, fuel, etc. How can we use wood products in a sustainable manner? You can do experiments that examine the growth time of different tree species to see which are good candidates for tree farming. Which types of lumber are most sustainable? You can also compare the effects of clear cutting vs. thinning a forested… Read more
EnvSci_p038
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Time Required Long (2-4 weeks)
Science Fair Project Idea
Many continents contain large mountain ranges that divide the continent into different regions. In the U.S. the Rocky Mountains mark the continental divide. The presence of a large mountain range can have a big effect on seasonal weather patterns. Also, the weather and climate on one side of a mountain range may be very different from weather and climate on the other side of the range. In the case of the Rocky Mountains, the western slope and eastern slope each have very different climates… Read more
Weather_p022
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Time Required Long (2-4 weeks)
Science Fair Project Idea
Survey your area to find out which species of plants and animals live there. You might be surprised to find out that something you grew up thinking was very common, is actually quite unique! For example, if you live in the great plains, then you may think that prairie dogs are a nuisance or a pest. Actually, some species of prairie dogs are only found here, and have a very important role for short and tall grass prairie ecosystems. The prairie dogs are an important part of the food-chain, and… Read more
EnvSci_p031
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Time Required Long (2-4 weeks)
Science Fair Project Idea
Divide a part of your garden into two equal plots, with each plot receiving equal amounts of sun. Cover one plot with two inches of organic mulch, such as compost or ground bark. Leave the other plot uncovered. Use the same amount of water for each plot for two or three weeks. At the beginning of the experiment, and at one-week intervals, dig down and check the soil in each plot for moisture content. Which plot holds water better? Which plot shows better plant growth? (McCausland, 2006) Read more
EnvEng_p021
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Time Required Very Long (1+ months)
Science Fair Project Idea
What is geomagnetism, and how does it affect the earth? Visit the USGS Geomagnetism program for more information about this invisible force (USGS, 2006). How is the earth's magnetic field patterned? Are the magnetic poles located at the exact North and South Pole? How can the fields be mapped on the Earth's surface? What is declination? Use the mapping tools to study changes in declination patterns over time. (USGS, 2006) Read more
Geo_p029
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Time Required Average (6-10 days)
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