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Others Like “Protein Structure and Function”

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Science Fair Project Idea
Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD () to submit your sequence for an analysis of its predicted 3-D structures based upon thermodynamics… Read more
BioChem_p023
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Some proteins are soluble in aqueous solutions and some are not. Insoluble proteins can be a problem because the proteins can form large aggregates in solution which are difficult to purify, crystallize, and use in experiments. Compare the amino acid sequence and 3-D structures of some soluble and insoluble proteins (Berman, 2000). Is the structure polar or non-polar, and how might this affect solubility? How do detergents make an insoluble protein more soluble? Investigate how this… Read more
BioChem_p018
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Time Required Long (2-4 weeks)
Prerequisites Basic introduction to chemistry
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Wind can make a cold day colder, or a hot day more pleasant. Use weather data to test the effect of wind on the temperature. How much of a change on the perceived temperature can the wind make? How is wind shear calculated? How can a wind barrier, like a wind breaker, keep you warm even if there is no insulating material? Build an instrument to measure wind speed or direction. (FI, 2006; GLOBE, 2006; NCAR, 2006; NOAA, 2006; Unisys, 2006; Weather Underground, 2006; WMO, 2006) Read more
Weather_p019
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Time Required Average (6-10 days)
Science Fair Project Idea
If you live in a humid environment, then you know that summer is not only hot, it is downright muggy. You can test the effect of humidity on temperature by measuring the temperature and humidity in your bathroom while running the shower. You can also use historical weather data to compare average seasonal temperatures in humid (e.g., Florida) and dry (e.g., Arizona) regions. How does humidity relate to temperature? Pressure? Why do humid environments tend to be coastal or tropical? How does… Read more
Weather_p017
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Time Required Average (6-10 days)
Science Fair Project Idea
Temperature also changes with latitude. As you move away from the equator, the temperature tends to decrease. Test this by comparing weather data from weather stations at different latitudes. (FI, 2006; GLOBE, 2006; NCAR, 2006; NOAA, 2006; Unisys, 2006; Weather Underground, 2006; WMO, 2006) Read more
Weather_p021
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Time Required Short (2-5 days)
Science Fair Project Idea
Antibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different… Read more
MicroBio_p021
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Time Required Long (2-4 weeks)
Prerequisites This project requires access to bacteria and antibiotics in a laboratory setting. A basic knowledge of how to work with bacteria is needed to complete this science fair project. Consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" HtmlText="Microbiology Techniques and Troubleshooting" #] guide for information on how to conduct microbiology experiments.
Material Availability Specialty items, like bacteria and the media to grow them on, can be ordered from such as .
Cost High ($100 - $150)
Safety Requires adult supervision in a laboratory setting. Use sterile technique. Read the before starting any experiments. may be necessary.
Science Fair Project Idea
Can you imagine Valentine's Day or Halloween without chocolate? Well, if you're a chocolate lover brace yourself for the bad news. According to the United States Department of Agriculture (USDA), "Worldwide demand for cacao now exceeds production." If there isn't enough cacao, the major raw ingredient for chocolate, then the chocolate supply will dwindle. Hang on! Before you start rushing to the store to buy all the chocolate you can get your hands on, a solution is already in the works. In… Read more
Genom_p021
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Time Required Long (2-4 weeks)
Prerequisites A high school level introductory biology course is a prerequisite for this science project.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
What is geomagnetism, and how does it affect the earth? Visit the USGS Geomagnetism program for more information about this invisible force (USGS, 2006). How is the earth's magnetic field patterned? Are the magnetic poles located at the exact North and South Pole? How can the fields be mapped on the Earth's surface? What is declination? Use the mapping tools to study changes in declination patterns over time. (USGS, 2006) Read more
Geo_p029
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Time Required Average (6-10 days)
Science Fair Project Idea
The same principles of geology that we use to investigate the Earth can also be applied to other planets. Visit the Astrogeology Research Program at the USGS to find out how information about the geology of other planets can be gathered (USGS, 2006). Can you make a map or model of another planet? What minerals are found on other planets? Which planets have similar composition to the earth? What kind of geological forces occur on other planets? Do other planets have earthquakes, landslides… Read more
Geo_p031
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Time Required Average (6-10 days)
Science Fair Project Idea
There are many types of construction materials used for wood-frame houses. Compare the different uses for and strengths of different building materials, e.g.: particle board, plywood, pine, oriented strand board (OSB), and drywall (gypsum board, SheetRock). The Science Buddies Materials Science Resource will be helpful for learning about different ways to measure material strength. You should be sure to use the same cross-sectional area of each material in order to make fair comparisons.… Read more
CE_p020
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Time Required Average (6-10 days)
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