Others Like “Catalytic RNA and Structure” (top 20 results)
In order to study individual biochemical compounds like proteins, DNA, or RNA, biochemists need to know how to purify these components from a complex mixture. This is especially important for biotechnology and pharmaceutical industries, which sell purified biochemicals as reagents or drugs to consumers. Do an experiment to purify DNA, RNA, or protein from a complex mixture (for purifying DNA, see the Science Buddies project Extracting Onion DNA). The source of the material can be a cell…
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All animals have a genome, but do they all have genome projects? Find out which animals are currently having their genomes sequenced and how much we know already. Whose genomes are already finished? Whose genomes are just getting started? Find out by doing some simple bioinformatics data digging!
Unlocking the three-dimensional structure of a protein is crucial to help scientists understand how it functions in our bodies and how it can cause devastating diseases if it becomes disrupted or interacts in the wrong way. However, figuring out the structure of a protein in three-dimensional space can be very challenging. Proteins are the functional units of our cells, and every protein is made up of a long chain of amino acids. Amino acids come in different shapes and sizes, and they have…
Animals come in all shapes and sizes, even humans. You can look up different statistics about different kinds of animals using the Internet: average body size, brain size, life expectancy and generation time are some examples. Is there a correlation between body size and life span? Is there a correlation between body size and brain size? Is there a correlation between body size and generation time? Is there a correlation between body size and the size of your footprint? (Comparative Mammalian…
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How a biological system functions is a consequence of the 3-D structures of biological macromolecules like proteins and protein complexes. Proteins can be categorized into different protein families based upon sequence, structure, and function. Typically, proteins in the same family have similar biochemical functions. You can investigate the structure of a protein by using protein databases (Entrez Protein, SwissProt, PDB) and 3-D computational models. You can compare the structures of…
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When you take medicine, it needs to dissolve in order to be passed into your bloodstream to have an effect. On the other hand, the drug needs to be packed into a small, dense pill to make it easier to swallow. How does the delivery method of a drug change how quickly it enters the bloodstream? Compare different brands of a drug to find out which brands dissolve the quickest. Does the pH of the stomach (which is usually between 1 and 2) matter? Compare coated to uncoated pills: does the coating…
Aerodynamics and Hockey: Does the Force of Drag Have an Effect on the Distance the Puck Will Travel?
Think of a way to launch the puck with a reproducible force, and examine the effect of launching the puck in different orientations on the distance it travels. For more information on the physics, see Haché, 2002.
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Think about mountain ranges, canyons, sand dunes, or any other interesting geological feature you may live near enough to visit. The surface of the Earth is always changing due to a balance of forces both above and below the surface. Below-surface forces cause the Earth's crust to be faulted, folded, tilted, and lifted. Above-surface forces are primarily due to the natural processes of weathering and erosion. Can you show the effects of these forces using scale models, demonstrations,…
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Try different wind turbine/propeller (chord length, pitch) designs by making models from balsa wood. Connect the spinning axle to a DC motor and measure the voltage produced across a resistor to measure power output. Use fan as wind source. (Judge, 2004)
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A magic square is an arrangement of numbers from 1 to n2 in an n x n matrix. In a magic square each number occurs exactly once such that the sum of the entries of any row, column, or main diagonal is the same. You can make several magic squares and investigate the different properties of the square. Can you make an algorithm for constructing a Magic Square? Can you show that the sum of the entries of any row, column, or main diagonal must be n(n2+1)/2? Are there any other hidden properties of a…
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