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Science Fair Project Idea
thumbnail All living things have DNA inside their cells. How do scientists extract the DNA from cells in order to study it? In this science experiment you can make your own DNA extraction kit from household chemicals and use it to extract DNA from strawberries. Read more
BioChem_p015
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Imagine that you want to create your own brand of colored candies. You know they would be a success if only you could figure out how to make a certain color, such as purple. How can you do this when government regulators have approved just a few food dyes? First, you will need to find out how your competitors make all of their colors from these few dyes. Do different candy brands use the same or different dyes? This can be figured out with gel electrophoresis, a technique commonly used in… Read more
BioChem_p039
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Time Required Short (2-5 days)
Prerequisites None
Material Availability This project requires a [# Link Name="BioChem_p039.1" Value="HtmlAnchor" #]. See the Materials and Equipment list for details.
Cost High ($100 - $150)
Safety Use caution when heating the agarose. Never connect more than five 9-volt (V) batteries together for this project.
Science Fair Project Idea
thumbnail In this project, you'll learn how to isolate DNA from onion cells, separating it from other cellular components in a manner that still preserves its structure and sequence. In the end, you'll have enough DNA to see with the unaided eye, and you'll be able to spool it to demonstrate its strand-like structure. Read more
BioChem_p001
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Time Required Average (6-10 days)
Material Availability Readily available
Cost Low ($20 - $50)
Science Fair Project Idea
thumbnail When biologists want to separate different pieces of DNA, RNA, or proteins they use a technique called gel electrophoresis. In this science project you'll build a gel electrophoresis chamber and use it to discover how many components are in different colors of food coloring dye. Read more
BioChem_p028
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Readily available
Cost Average ($50 - $100)
Safety No issues
Science Fair Project Idea
thumbnail Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more
BioChem_p034
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Time Required Average (6-10 days)
Prerequisites Prior to starting this science fair project, you should either know how to use a spectrophotometer, or have access to someone who can show you how to use it.
Material Availability This science fair project requires access to laboratory equipment and supplies, including a spectrophotometer; see the Materials and Equipment section for more details. Access to a dairy is also needed for the main project, but the Variations section, below, lists options that are not dependent on dairy access.
Cost Very High (over $150)
Safety Adult supervision is recommended when using laboratory equipment.
Science Fair Project Idea
Is it possible to manipulate bacteria to become protein production factories? Can diabetics control blood glucose with insulin produced by bacteria? How cool would it be to take advantage of these microorganism's sophisticated makeup, short doubling times and cheap growth media to mass produce medically and commercially useful proteins? All of these are possible with a few simple genetic manipulations. By the end of this project you would know the basic foundation on which many… Read more
BioChem_p013
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipets all helpful.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Requires adult supervision in a laboratory facility. For ISEF-affiliated fairs, this project will require [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC" #] approval.
Science Fair Project Idea
thumbnail Native plants are important for both ecological and medicinal reasons. However, most native plants are not very well studied. One way to know more about these plants is to understand which other species of plants they are most closely related to. In this science project you will sequence part of the chloroplast genome from a native plant and use this information to determine its evolutionary relationship to other species of plants. If the plant you chose has not been sequenced before, you can… Read more
Genom_p012
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Time Required Long (2-4 weeks)
Prerequisites High school biology class; familiarity with using the PCR machine and gel electrophoresis equipment, and/or using the equipment with a mentor.
Material Availability You will need specialized pieces of equipment, including a PCR machine (thermocycler) and a gel electrophoresis apparatus. If your school does not have this equipment you might want to seek out a mentor at a junior college, university, or biotechnology company. If you have the resources you can do the DNA sequencing yourself, otherwise you can send the samples to Dr. Baysdorfer at California State University, East Bay, see Experimental Procedure for more details.
Cost High ($100 - $150)
Safety This project uses ethidium bromide, which is a carcinogen. Always wear gloves and safety goggles when handling. Dispose of the ethidium bromide according to your school or institute's hazardous waste protocols. If you have concerns, ask your teacher or mentor for advice.
Science Fair Project Idea
thumbnail Have you ever had a cut or a bloody nose that seemed like it would bleed forever? Though it might have seemed like a long time, it probably did stop pretty quickly. This is because different factors in a person's blood normally work together to plug the opening caused by the cut in a process called blood clotting or coagulation. However, some people have a genetic disorder called hemophilia that causes them to bleed excessively. If a person has hemophilia, he or she is usually missing some of… Read more
HumBio_p037
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Specific chemicals (sodium citrate, sodium alginate, and calcium chloride) are needed. A kit containing these chemicals is available from the Science Buddies Store. See the Materials tab for details.
Cost Low ($20 - $50)
Safety Adult supervision may be needed for using a blender. All chemicals in this science project are safe to use (they are common food additives).
Science Fair Project Idea
thumbnail Quick, what is your favorite color of M&Ms® candy? Do you want to know what dyes were used to make that color? Check out this science project to find out how you can do some scientific detective work to find out for yourself. Read more
FoodSci_p006
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Time Required Short (2-5 days)
Prerequisites None
Material Availability A few specialty items are needed; see the Materials tab.
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
thumbnail Do you like reading detective stories or watching crime shows on TV? This advanced project idea in the area of forensic science might be right for you. Read more
BioChem_p009
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Time Required Average (6-10 days)
Prerequisites High School Biology
Material Availability This project requires you to order specialty items and have access to some laboratory equipment, see the Materials & Equipment section for more details.
Cost High ($100 - $150)
Safety No issues
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