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Others Like “A Prescription for Success: Drugs & Your Genetics”

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Science Fair Project Idea
thumbnail In a survey conducted from 2007 to 2010, the U.S. Centers for Disease Control and Prevention reported that about 49% of people in the United States had taken at least one prescription drug during the past month, and about 22% of people had taken three or more prescription drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic… Read more
BioMed_p006
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Find out the real explanation for why your parents are so weird! Here is a science project that lets you explore the internet to find out why your "DNA blueprint" is so important to health and disease. In this science project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Our genes are made up of hundreds to millions of building blocks, called DNA nucleotides, and if just a single nucleotide of DNA becomes mutated it might cause a devastating genetic disease. But sometimes a mutation actually does no damage. What kinds of mutations have to occur to cause a genetic disease? In this science project, you will explore online genetic databases to identify how a mutation in a gene can result in a dysfunctional protein, and how other mutations may have no effect… Read more
BioMed_p007
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD () to submit your sequence for an analysis of its predicted 3-D structures based upon thermodynamics… Read more
BioChem_p023
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Did you ever wonder about your ancient ancestors? Who they were? Where they came from? In this science project, you will investigate the secrets of your distant past as revealed by your DNA. In order to obtain a sample for DNA analysis, you will scrape a soft swab inside your mouth to collect cheek cells. The cheek cell sample will be sent to a lab for processing, and the results of the analysis will be sent to you. Based on the genetic markers in your DNA, the ancient clan that your… Read more
Genom_p014
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Time Required Very Long (1+ months)
Prerequisites You should be familiar with the concepts of basic human genetics.
Material Availability Readily available
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
thumbnail Have you ever wondered how X-rays affect living organisms? You have probably had X-rays taken at the dentist's or doctor's office. These X-rays are considered to be relatively safe, but every X-ray exposes a person to some radiation, specifically electromagnetic radiation. Radiation is energy that travels through space as either waves or high speed particles. Watch this video to learn more about electromagnetic radiation. Watch this video which gives an introduction to… Read more
MicroBio_p030
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Time Required Long (2-4 weeks)
Prerequisites Basic understanding of what radiation, DNA, and mutations are.
Material Availability See How to Build an X-ray Machine for a detailed list of materials that will need to be ordered.
Cost Very High (over $150)
Safety See Introduction to Radiation & Radiation Safety for safety information.
Science Fair Project Idea
thumbnail Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science project,… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Unlocking the three-dimensional structure of a protein is crucial to help scientists understand how it functions in our bodies and how it can cause devastating diseases if it becomes disrupted or interacts in the wrong way. However, figuring out the structure of a protein in three-dimensional space can be very challenging. Proteins are the functional units of our cells, and every protein is made up of a long chain of amino acids. Amino acids come in different shapes and sizes, and they have… Read more
BioMed_p008
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Time Required Long (2-4 weeks)
Prerequisites Understanding of what proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Want to send coded messages to your friends? Can you write a simple letter-substitution encryption program in JavaScript? How easy is it to break the simple code? Can you write a second program that "cracks" the letter-substitution code? Investigate other encryption schemes. What types of encryption are least vulnerable to attack? Read more
CompSci_p031
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Time Required Long (2-4 weeks)
Science Fair Project Idea
In order to study individual biochemical compounds like proteins, DNA, or RNA, biochemists need to know how to purify these components from a complex mixture. This is especially important for biotechnology and pharmaceutical industries, which sell purified biochemicals as reagents or drugs to consumers. Do an experiment to purify DNA, RNA, or protein from a complex mixture (for purifying DNA, see the Science Buddies project ). The source of the material can be a cell line, bacterial culture,… Read more
BioChem_p026
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Time Required Average (6-10 days)
Material Availability Most items are readily available; any specialty items needed can be ordered from [# ProjectGuide Name="Advanced.ApprovedSuppliers" Value="HtmlAnchor" HtmlText="online vendors" #].
Cost Average ($50 - $100)
Safety If bacteria or cell lines are used as the source of material for purification, [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary. Adult supervision is recommended.
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