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Others Like “From Genes to Genetic Diseases: What Kinds of Mutations Matter?”

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Science Fair Project Idea
thumbnail In a survey conducted from 2007 to 2010, the U.S. Centers for Disease Control and Prevention reported that about 49% of people in the United States had taken at least one prescription drug during the past month, and about 22% of people had taken three or more prescription drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic… Read more
BioMed_p006
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Find out the real explanation for why your parents are so weird! Here is a science project that lets you explore the internet to find out why your "DNA blueprint" is so important to health and disease. In this science project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science project,… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
BioMed_p009
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Time Required Short (2-5 days)
Prerequisites Basic understanding of how genes are turned into proteins.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more
Genom_p002
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Time Required Long (2-4 weeks)
Prerequisites High School Biology, excellent computer skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Have you ever known someone who had a bad reaction to a prescription drug? Although pharmaceutical companies test new drugs on a large number of people to make sure the drug works the way it is supposed to, often a small percentage of people respond differently to the drug. A person's genetics plays a large role in determining his or her response to a given drug. Our genes are made up of hundreds to millions of nucleotides of DNA (deoxyribonucleic acid), the genetic code. If just a… Read more
BioMed_p005
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Time Required Very Long (1+ months)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability After 23andMe receives your sample, your results should be ready in 6-8 weeks. Alternatively, you can do this science project using a readily available free demo account on 23andMe.
Cost Very High (over $150)
Safety No issues
Science Fair Project Idea
thumbnail Have you ever experienced heartburn after eating a large, greasy meal? Or have you heard of someone complaining about heartburn pains? It's very common; over 60 million people in the U.S. have heartburn at least once every month. Heartburn pain usually results from stomach acids escaping from the stomach and irritating the esophagus above it. Luckily, there are medical drugs, called antacids, which can help relieve heartburn pain. But how do antacids work, and how effective are they? In this… Read more
BioMed_p010
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety Wear safety goggles and gloves and have an adult help you when handling and working with the artificial stomach acid solution. Hydrochloric acid is corrosive to hands and eyes.
Science Fair Project Idea
Remember going to the doctor and getting vaccine shots? It is no fun getting poked with a needle, but fortunately, a vaccine gives you protection against a serious illness for years to come. But what about the flu vaccine? How come there is a new one every year? This science fair project will show you why. Read more
Genom_p003
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Time Required Average (6-10 days)
Prerequisites Excellent computer skills. Basic understanding of immunology and protein sequences or willingness to learn about these topics.
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Chemicals from Earth's atmosphere are making their way down to the planet! Not in spaceships, but in rain. The acid rain can infiltrate ground water, lakes, and streams. How does acid rain affect aquatic ecosystems? Read more
EnvSci_p016
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Time Required Average (6-10 days)
Prerequisites None.
Material Availability Items will need to be special ordered. See the Materials and Equipment section for more details.
Cost Average ($50 - $100)
Safety No hazards.
Science Fair Project Idea
thumbnail What color is grape soda? If you pour it into a clear glass you can easily see it is purple, but that is usually not its natural color. Manufacturers add red and blue dye to the soda. The dyes mix together and you get purple soda. What if you wanted to un-mix the dyes, could you? Yes! In a chemistry laboratory, using a technique called column chromatography, you could separate the two dyes again. But what about at home, can you use low-tech supplies to do the same thing? In this science… Read more
BioChem_p045
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Syringes (without needles) and Space Sand need to be specially ordered. See the Materials and Equipment list for details.
Cost Low ($20 - $50)
Safety Use caution and follow all safety warnings when handling and using the 70% isopropyl alcohol. The alcohol is highly flammable. Do not swallow, and avoid any contact with eyes.
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