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Others Like “From Genes to Genetic Diseases: What Kinds of Mutations Matter?”

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Science Fair Project Idea
In a survey conducted from 2007 to 2010, the U.S. Centers for Disease Control and Prevention reported that about 49% of people in the United States had taken at least one prescription drug during the past month, and about 22% of people had taken three or more prescription drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic… Read more
BioMed_p006
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Find out the real explanation for why your parents are so weird! Here is a science project that lets you explore the internet to find out why your "DNA blueprint" is so important to health and disease. In this science project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
BioMed_p009
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Time Required Short (2-5 days)
Prerequisites Basic understanding of how genes are turned into proteins.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science project,… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
What color is grape soda? If you pour it into a clear glass you can easily see it is purple, but that is usually not its natural color. Manufacturers add red and blue dye to the soda. The dyes mix together and you get purple soda. What if you wanted to un-mix the dyes, could you? Yes! In a chemistry laboratory, using a technique called column chromatography, you could separate the two dyes again. But what about at home, can you use low-tech supplies to do the same thing? In this science… Read more
BioChem_p045
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Syringes (without needles) and Space Sand need to be specially ordered. See the Materials and Equipment list for details.
Cost Low ($20 - $50)
Safety Use caution and follow all safety warnings when handling and using the 70% isopropyl alcohol. The alcohol is highly flammable. Do not swallow, and avoid any contact with eyes.
Science Fair Project Idea
Remember going to the doctor and getting vaccine shots? It is no fun getting poked with a needle, but fortunately, a vaccine gives you protection against a serious illness for years to come. But what about the flu vaccine? How come there is a new one every year? This science fair project will show you why. Read more
Genom_p003
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- Less Details
Time Required Average (6-10 days)
Prerequisites Excellent computer skills. Basic understanding of immunology and protein sequences or willingness to learn about these topics.
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Can you remember what the weather was like last week? Last year? Here's a project that looks at what the weather was like for over a hundred years. You'll use historical climate data to look at moisture conditions in regions across the continental U.S. You'll use a spreadsheet program to calculate the frequency of different moisture conditions for each region and make graphs for comparison. Which part of the country has the most frequent droughts? The most frequent periods of prolonged… Read more
Weather_p005
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Time Required Short (2-5 days)
Prerequisites Computer with Internet access and a spreadsheet program (e.g., Excel)
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
In the wild there are two types of animals: the hunters and the hunted. A good predator is always on the prowl for fresh prey. What can an animal do to stay off of the menu? To survive, some animals use camouflage so they can better blend in with their surroundings. In this science project, you will be the hungry predator hunting for M&M® prey. But it may not be as easy as it sounds — some of your prey will be camouflaged by their habitat. Will they be able to avoid your grasp? … Read more
Zoo_p012
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily Available
Cost Very Low (under $20)
Safety No hazards
Science Fair Project Idea
Have you ever seen a tortoiseshell cat? "What kind of cat is that?" you might ask. A tortoiseshell cat has two different fur colors, black or brown and red or orange. The gene that gives rise to the red or orange fur color is on the X chromosome. And did you know that most tortoiseshell cats are female? That's because female cats have two X chromosomes, while males only have one, which allows the females to express two different color combinations! Try this science fair project to figure out… Read more
MamBio_p022
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Time Required Short (2-5 days)
Prerequisites You should have a basic understanding of genetic principles.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The human kidney is the most commonly transplanted organ in the United States, numbering more than 17,000 transplants in 2010 alone! But kidney transplantation technology faces a lot of challenges, including a shortage of kidney donors and the need for recipients to take immunosuppressant drugs to keep their bodies from rejecting a transplanted kidney. In this science project, with the help of bioinformatics databases, you will explore how a kidney could be bioengineered using stem cells,… Read more
BioMed_p013
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- Less Details
Time Required Short (2-5 days)
Prerequisites An advanced biology course or equivalent understanding of how cells respond to environmental stimuli and signaling pathways.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
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