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Project Idea
thumbnail Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail From 2005 to 2008, 48% of everyone in the U.S. was using at least one prescription drug, and 21% of people were taking three or more drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic mutations associated with a different response to a drug? In this science project, you will explore an online drug and genetics database to… Read more
BioMed_p006
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail Our genes are made up of hundreds to millions of building blocks, called DNA nucleotides, and if just a single nucleotide of DNA becomes mutated it might cause a devastating genetic disease. But sometimes a mutation actually does no damage. What kinds of mutations have to occur to cause a genetic disease? In this science project, you will explore online genetic databases to identify how a mutation in a gene can result in a dysfunctional protein, and how other mutations may have no… Read more
BioMed_p007
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail The human kidney is the most commonly transplanted organ in the United States, numbering more than 17,000 transplants in 2010 alone! But kidney transplantation technology faces a lot of challenges, including a shortage of kidney donors and the need for recipients to take immunosuppressant drugs to keep their bodies from rejecting a transplanted kidney. In this science project, with the help of bioinformatics databases, you will explore how a kidney could be bioengineered using stem cells,… Read more
BioMed_p013
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Time Required Short (2-5 days)
Prerequisites An advanced biology course or equivalent understanding of how cells respond to environmental stimmuli and signaling pathways.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
BioMed_p009
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Time Required Short (2-5 days)
Prerequisites Basic understanding of how genes are turned into proteins.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
Have you ever played a video game and gotten so involved that you felt as if you were living inside the game? What were the characteristics of the game that made you feel part of the action? One component of an absorbing video game is an onscreen world that makes sense—a world that takes physics into account. A game in which the player feels the effect of trudging through mud, slipping on ice, or catapulting a bird is more fun than one with no environmental interaction. In this… Read more
Games_p031
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Time Required Very Long (1+ months)
Prerequisites You should be comfortable programming in C++ language, familiar with the GameMaker software package, and able to program in GameMaker Language (GML). You should completely review and understand all the GameMaker tutorials and examples listed in the Science Buddies GameMaker User Guide and in the Tutorials section of YoYo Games Wiki.
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Project Idea
thumbnail You have most likely witnessed the change that occurs as a banana ripens It changes from green and relatively hard to yellow and soft. The flavor also changes, from bitter to sweet. What happens during ripening? One big change is the increase in sugar content. In this food science fair project, you will measure how the sugar content of a banana changes as it ripens. Read more
FoodSci_p063
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Time Required Average (6-10 days)
Prerequisites You will need both ripe and unripe bananas for this science fair project, so be sure you can find them in your grocery store, particularly if it's the off-season.
Material Availability You will need to purchase a refractometer online. See the Materials and Equipment list for details.
Cost High ($100 - $150)
Safety No issues
Project Idea
thumbnail You have probably seen figures showing how human beings are related to chimpanzees, gorillas, and other primates. In this genomics science fair project, you will use bioinformatics tools to generate your own primate family tree. Read more
Genom_p019
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Time Required Average (6-10 days)
Prerequisites High school genetics
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Project Idea
thumbnail Enzymes speed up chemical reactions by factors of at least a million. Now that's acceleration! This project investigates how temperature affects how fast these enzymatic reactions occur. Read more
BioChem_p011
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Must have access to a stove, refrigerator, and a freezer.
Cost Average ($50 - $100)
Safety Use caution when handling the hydrogen peroxide, boiling water, stove, and blender. Adult supervision may be required for using the stove.
Project Idea
Have you ever wondered about the various types of music in a video game you've played? You may not have paid much attention to the music, but its job was to enhance your gaming experience. In fact, the wrong kind of music can detract from the atmosphere of the game. Can you imagine the music in Mario KartTM playing in Street Fighter®? In a game, music can indicate many different things, such as a special or new event, shift of mood, or the arrival of a character. This kind of music is… Read more
Games_p030
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
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