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Science Fair Project Idea
thumbnail Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail From 2005 to 2008, 48% of everyone in the U.S. was using at least one prescription drug, and 21% of people were taking three or more drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic mutations associated with a different response to a drug? In this science project, you will explore an online drug and genetics database to… Read more
BioMed_p006
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Our genes are made up of hundreds to millions of building blocks, called DNA nucleotides, and if just a single nucleotide of DNA becomes mutated it might cause a devastating genetic disease. But sometimes a mutation actually does no damage. What kinds of mutations have to occur to cause a genetic disease? In this science project, you will explore online genetic databases to identify how a mutation in a gene can result in a dysfunctional protein, and how other mutations may have no… Read more
BioMed_p007
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail The human kidney is the most commonly transplanted organ in the United States, numbering more than 17,000 transplants in 2010 alone! But kidney transplantation technology faces a lot of challenges, including a shortage of kidney donors and the need for recipients to take immunosuppressant drugs to keep their bodies from rejecting a transplanted kidney. In this science project, with the help of bioinformatics databases, you will explore how a kidney could be bioengineered using stem cells,… Read more
BioMed_p013
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Time Required Short (2-5 days)
Prerequisites An advanced biology course or equivalent understanding of how cells respond to environmental stimmuli and signaling pathways.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Have you ever played a video game and gotten so involved that you felt as if you were living inside the game? What were the characteristics of the game that made you feel part of the action? One component of an absorbing video game is an onscreen world that makes sense—a world that takes physics into account. A game in which the player feels the effect of trudging through mud, slipping on ice, or catapulting a bird is more fun than one with no environmental interaction. In this… Read more
Games_p031
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Time Required Very Long (1+ months)
Prerequisites You should be comfortable programming in C++ language, familiar with the GameMaker software package, and able to program in GameMaker Language (GML). You should completely review and understand all the GameMaker tutorials and examples listed in the Science Buddies GameMaker User Guide and in the Tutorials section of YoYo Games Wiki.
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
thumbnail You have most likely witnessed the change that occurs as a banana ripens It changes from green and relatively hard to yellow and soft. The flavor also changes, from bitter to sweet. What happens during ripening? One big change is the increase in sugar content. In this food science fair project, you will measure how the sugar content of a banana changes as it ripens. Read more
FoodSci_p063
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Time Required Average (6-10 days)
Prerequisites You will need both ripe and unripe bananas for this science fair project, so be sure you can find them in your grocery store, particularly if it's the off-season.
Material Availability You will need to purchase a refractometer online. See the Materials and Equipment list for details.
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
thumbnail Find out the real explanation for why your parents are so weird! Here is a project that lets you explore "the net" to find out why your "DNA blueprint" is so important to health and disease. In this project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Some proteins are soluble in aqueous solutions and some are not. Insoluble proteins can be a problem because the proteins can form large aggregates in solution which are difficult to purify, crystallize, and use in experiments. Compare the amino acid sequence and 3-D structures of some soluble and insoluble proteins (Berman, 2000). Is the structure polar or non-polar, and how might this affect solubility? How do detergents make an insoluble protein more soluble? Investigate how this… Read more
BioChem_p018
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Time Required Long (2-4 weeks)
Prerequisites Basic introduction to chemistry
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more
BioChem_p034
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Time Required Average (6-10 days)
Prerequisites Prior to starting this science fair project, you should either know how to use a spectrophotometer, or have access to someone who can show you how to use it.
Material Availability This science fair project requires access to laboratory equipment and supplies, including a spectrophotometer; see the Materials and Equipment section for more details. Access to a dairy is also needed for the main project, but the Variations section, below, lists options that are not dependent on dairy access.
Cost Very High (over $150)
Safety Adult supervision is recommended when using laboratory equipment.
Science Fair Project Idea
thumbnail In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
BioMed_p009
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Time Required Short (2-5 days)
Prerequisites Basic understanding of how genes are turned into proteins.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
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