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Others Like “Computational Exploration of Protein Function”

Project Idea
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use Web-based computer… Read more
Genom_p001
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Time Required Average (6-10 days)
Prerequisites High School Biology, excellent website navigation skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Project Idea
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use a Web-based… Read more
Genom_p004
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Time Required Very Short (≤ 1 day)
Prerequisites You should have studied Life Science or Biology and also need good website navigation skills.
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail Woolly mammoths shook the ground of ice-age tundras for millennia, living next to saber tooth tigers and prehistoric man. Although they have been extinct for thousands of years, scientists continue to learn more and more about this mighty animal. Some of the most exciting new research is being produced by looking at DNA extracted from the hair and bones of woolly mammoths entombed in ice. In this genomics science fair project, you will use bioinformatics tools to determine the woolly mammoth's… Read more
Genom_p016
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Time Required Short (2-5 days)
Prerequisites You should be familiar with basic biological concepts, including DNA, proteins, and mutations.
Material Availability Must have access to the Internet.
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail Believe it or not, scientists were recently able to recover tissue from a 68-million-year-old Tyrannosaurus rex fossil! Not only were they able to purify non-mineralized tissue, but they also succeeded in obtaining partial sequence information for protein molecules in the T. rex tissue. In this genomics science fair project, you will use the T. rex's protein sequence to search sequence databases for the its closest living relatives. Read more
Genom_p018
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Project Idea
thumbnail You have probably seen figures showing how human beings are related to chimpanzees, gorillas, and other primates. In this genomics science fair project, you will use bioinformatics tools to generate your own primate family tree. Read more
Genom_p019
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Time Required Average (6-10 days)
Prerequisites High school genetics
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Project Idea
thumbnail Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail Find out the real explanation for why your parents are so weird! Here is a project that lets you explore "the net" to find out why your "DNA blueprint" is so important to health and disease. In this project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail The first land animals took their tentative steps out of the ocean and onto solid ground around 365 million years ago. Over millions of years, these early ancestors developed into tetrapods, including amphibians, reptiles, dinosaurs, birds, and mammals. Then, around 50 million years ago, the reverse process occurred: the mammalian ancestor of today’s whales returned to the ocean. In this genomics science fair project, you will use mitochondrial protein sequencing to trace the evolution of… Read more
Genom_p017
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Time Required Average (6-10 days)
Prerequisites You should be familiar with high school level genetics (DNA, protein, mutations).
Material Availability Readily available.
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail Our genes are made up of hundreds to millions of building blocks, called DNA nucleotides, and if just a single nucleotide of DNA becomes mutated it might cause a devastating genetic disease. But sometimes a mutation actually does no damage. What kinds of mutations have to occur to cause a genetic disease? In this science project, you will explore online genetic databases to identify how a mutation in a gene can result in a dysfunctional protein, and how other mutations may have no… Read more
BioMed_p007
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail From 2005 to 2008, 48% of everyone in the U.S. was using at least one prescription drug, and 21% of people were taking three or more drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic mutations associated with a different response to a drug? In this science project, you will explore an online drug and genetics database to… Read more
BioMed_p006
+ More Details
- Less Details
Time Required Short (2-5 days)
Prerequisites Basic understanding of what genes, DNA, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
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