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Others Like “Who Has the Biggest Genome?”

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Science Fair Project Idea
thumbnail Have you ever tried to pack a suitcase? If so, you know that no matter how hard you try, there is a limit to the amount you can cram in, which means if you have more stuff, you need a bigger suitcase! Do you think the same principle applies to DNA in a cell? Does an animal with a bigger genome need a larger cell nucleus to store its DNA? Try this science project and find out! Read more
Genom_p013
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Time Required Short (2-5 days)
Prerequisites None
Material Availability This science fair project requires the use of a computer with Internet access.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail All animals have a genome, but do they all have genome projects? Find out which animals are currently having their genomes sequenced and how much we know already. Whose genomes are already finished? Whose genomes are just getting started? Find out by doing some simple bioinformatics data digging! Read more
Genom_p007
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use Web-based computer… Read more
Genom_p001
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Time Required Average (6-10 days)
Prerequisites High School Biology, excellent website navigation skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Do you like solving mysteries? In this experiment, you can find out how a DNA fingerprint can help you figure out whodunit. The answer might just be in the "sequence" of events! Read more
BioChem_p016
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail How do scientists "copy" DNA? They use a process called the Polymerase Chain Reaction, or PCR. The key to making this process work is having a short piece of DNA, called a primer, that will stick to the larger piece of DNA you want to copy, called a template. In this science project, you will test how the number of matches and mismatches in a primer will affect its ability to stick, or anneal, to the DNA template during PCR. Read more
BioChem_p017
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability A large number of magnets are needed.
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
thumbnail Find out the real explanation for why your parents are so weird! Here is a science project that lets you explore the internet to find out why your "DNA blueprint" is so important to health and disease. In this science project you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
Genom_p008
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Time Required Average (6-10 days)
Prerequisites A good knowledge of basic concepts in genetics and good computer database searching skills
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change the sequence of the DNA. Will the same enzymes still cut the new DNA sequence? Read more
BioChem_p014
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Woolly mammoths shook the ground of ice-age tundras for millennia, living next to saber tooth tigers and prehistoric man. Although they have been extinct for thousands of years, scientists continue to learn more and more about this mighty animal. Some of the most exciting new research is being produced by looking at DNA extracted from the hair and bones of woolly mammoths entombed in ice. In this genomics science fair project, you will use bioinformatics tools to determine the woolly mammoth's… Read more
Genom_p016
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Time Required Short (2-5 days)
Prerequisites You should be familiar with basic biological concepts, including DNA, proteins, and mutations.
Material Availability Must have access to the Internet.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more
Genom_p002
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Time Required Long (2-4 weeks)
Prerequisites High School Biology, excellent computer skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Native plants are important for both ecological and medicinal reasons. However, most native plants are not very well studied. One way to know more about these plants is to understand which other species of plants they are most closely related to. In this science project you will sequence part of the chloroplast genome from a native plant and use this information to determine its evolutionary relationship to other species of plants. If the plant you chose has not been sequenced before, you can… Read more
Genom_p012
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Time Required Long (2-4 weeks)
Prerequisites High school biology class; familiarity with using the PCR machine and gel electrophoresis equipment, and/or using the equipment with a mentor.
Material Availability You will need specialized pieces of equipment, including a PCR machine (thermocycler) and a gel electrophoresis apparatus. If your school does not have this equipment you might want to seek out a mentor at a junior college, university, or biotechnology company. If you have the resources you can do the DNA sequencing yourself, otherwise you can send the samples to Dr. Baysdorfer at California State University, East Bay, see Experimental Procedure for more details.
Cost High ($100 - $150)
Safety This project uses ethidium bromide, which is a carcinogen. Always wear gloves and safety goggles when handling. Dispose of the ethidium bromide according to your school or institute's hazardous waste protocols. If you have concerns, ask your teacher or mentor for advice.
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