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Others Like “Bioinformatics - The Perfect Marriage of Computer Science & Medicine”

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Science Fair Project Idea
Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD () to submit your sequence for an analysis of its predicted 3-D structures based upon thermodynamics… Read more
BioChem_p023
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The first land animals took their tentative steps out of the ocean and onto solid ground around 365 million years ago. Over millions of years, these early ancestors developed into tetrapods, including amphibians, reptiles, dinosaurs, birds, and mammals. Then, around 50 million years ago, the reverse process occurred: the mammalian ancestor of today's whales returned to the ocean. In this genomics science fair project, you will use mitochondrial protein sequencing to trace the evolution of… Read more
Genom_p017
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Time Required Average (6-10 days)
Prerequisites You should be familiar with high school level genetics (DNA, protein, mutations).
Material Availability Readily available.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use a Web-based… Read more
Genom_p004
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Time Required Very Short (≤ 1 day)
Prerequisites You should have studied Life Science or Biology and also need good website navigation skills.
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Did you ever wonder about your ancient ancestors? Who they were? Where they came from? In this science project, you will investigate the secrets of your distant past as revealed by your DNA. In order to obtain a sample for DNA analysis, you will scrape a soft swab inside your mouth to collect cheek cells. The cheek cell sample will be sent to a lab for processing, and the results of the analysis will be sent to you. Based on the genetic markers in your DNA, the ancient clan that your… Read more
Genom_p014
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Time Required Very Long (1+ months)
Prerequisites You should be familiar with the concepts of basic human genetics.
Material Availability Readily available
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
Do you like reading detective stories or watching crime shows on TV? This advanced project idea in the area of forensic science might be right for you. Read more
BioChem_p009
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Time Required Average (6-10 days)
Prerequisites High School Biology
Material Availability This project requires you to order specialty items and have access to some laboratory equipment, see the Materials & Equipment section for more details.
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
The human kidney is the most commonly transplanted organ in the United States, numbering more than 17,000 transplants in 2010 alone! But kidney transplantation technology faces a lot of challenges, including a shortage of kidney donors and the need for recipients to take immunosuppressant drugs to keep their bodies from rejecting a transplanted kidney. In this science project, with the help of bioinformatics databases, you will explore how a kidney could be bioengineered using stem cells,… Read more
BioMed_p013
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Time Required Short (2-5 days)
Prerequisites An advanced biology course or equivalent understanding of how cells respond to environmental stimuli and signaling pathways.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Believe it or not, scientists were recently able to recover tissue from a 68-million-year-old Tyrannosaurus rex fossil! Not only were they able to purify non-mineralized tissue, but they also succeeded in obtaining partial sequence information for protein molecules in the T. rex tissue. In this genomics science fair project, you will use the T. rex's protein sequence to search sequence databases for the its closest living relatives. Read more
Genom_p018
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
All animals have a genome, but do they all have genome projects? Find out which animals are currently having their genomes sequenced and how much we know already. Whose genomes are already finished? Whose genomes are just getting started? Find out by doing some simple bioinformatics data digging! Read more
Genom_p007
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
BioMed_p009
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Time Required Short (2-5 days)
Prerequisites Basic understanding of how genes are turned into proteins.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Unlocking the three-dimensional structure of a protein is crucial to help scientists understand how it functions in our bodies and how it can cause devastating diseases if it becomes disrupted or interacts in the wrong way. However, figuring out the structure of a protein in three-dimensional space can be very challenging. Proteins are the functional units of our cells, and every protein is made up of a long chain of amino acids. Amino acids come in different shapes and sizes, and they have… Read more
BioMed_p008
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Time Required Long (2-4 weeks)
Prerequisites Understanding of what proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
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