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Science Fair Project Idea
thumbnail When biologists want to separate different pieces of DNA, RNA, or proteins they use a technique called gel electrophoresis. In this science project you'll build a gel electrophoresis chamber and use it to discover how many components are in different colors of food coloring dye. Read more
BioChem_p028
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Readily available
Cost Average ($50 - $100)
Safety No issues
Science Fair Project Idea
thumbnail Have your favorite foods been genetically modified? Genetically modified (GM) foods do not require labeling in the USA, and foods with less than 5% content from genetically modified organisms (GMOs) can be labeled "GMO free." In Europe and Asia, GM foods require labeling only if they contain more than 1% GM content. You can investigate whether your favorite food products, like corn tortilla chips, are made from genetically modified organisms using the from the Bio-Rad Biotechnology Explorer… Read more
BioChem_p025
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Time Required Average (6-10 days)
Prerequisites Access to a research laboratory with PCR equipment is required for this project.
Material Availability Requires purchase of Bio-Rad's [# Link Name="BioChem_p025.1" Value="HtmlAnchor" #]. A teacher's help is needed to order as Bio-Rad sells directly to schools.
Cost Very High (over $150)
Safety Adult supervision is required in the laboratory facility.
Science Fair Project Idea
thumbnail How do scientists "copy" DNA? They use a process called the Polymerase Chain Reaction, or PCR. The key to making this process work is having a short piece of DNA, called a primer, that will stick to the larger piece of DNA you want to copy, called a template. In this science project, you will test how the number of matches and mismatches in a primer will affect its ability to stick, or anneal, to the DNA template during PCR. Read more
BioChem_p017
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Time Required Very Short (≤ 1 day)
Prerequisites None
Material Availability A large number of magnets are needed.
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
thumbnail Imagine that you want to create your own brand of colored candies. You know they would be a success if only you could figure out how to make a certain color, such as purple. How can you do this when government regulators have approved just a few food dyes? First, you will need to find out how your competitors make all of their colors from these few dyes. Do different candy brands use the same or different dyes? This can be figured out with gel electrophoresis, a technique commonly used in… Read more
BioChem_p039
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Time Required Short (2-5 days)
Prerequisites None
Material Availability This project requires a [# Link Name="BioChem_p039.1" Value="HtmlAnchor" #]. See the Materials and Equipment list for details.
Cost High ($100 - $150)
Safety Use caution when heating the agarose. Never connect more than five 9-volt (V) batteries together for this project.
Science Fair Project Idea
thumbnail Do you like reading detective stories or watching crime shows on TV? This advanced project idea in the area of forensic science might be right for you. Read more
BioChem_p009
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Time Required Average (6-10 days)
Prerequisites High School Biology
Material Availability This project requires you to order specialty items and have access to some laboratory equipment, see the Materials & Equipment section for more details.
Cost High ($100 - $150)
Safety No issues
Science Fair Project Idea
The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more
Genom_p002
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Time Required Long (2-4 weeks)
Prerequisites High School Biology, excellent computer skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use Web-based computer… Read more
Genom_p001
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Time Required Average (6-10 days)
Prerequisites High School Biology, excellent website navigation skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more
BioChem_p036
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability You will need to order a UV-sensitive yeast kit online. See the Materials and Equipment list for details. Note: You might have to have the yeast delivered to a school if the company does not deliver to residential addresses.
Cost High ($100 - $150)
Safety Pouring hot agar plates should be done with caution.
Science Fair Project Idea
thumbnail Is it possible to manipulate bacteria to become protein production factories? Can diabetics control blood glucose with insulin produced by bacteria? How cool would it be to take advantage of these microorganism's sophisticated makeup, short doubling times and cheap growth media to mass produce medically and commercially useful proteins? All of these are possible with a few simple genetic manipulations. By the end of this project you would know the basic foundation on which many… Read more
BioChem_p013
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipets all helpful.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Requires adult supervision in a laboratory facility. For ISEF-affiliated fairs, this project will require [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC" #] approval.
Science Fair Project Idea
thumbnail In this project, you'll learn how to isolate DNA from onion cells, separating it from other cellular components in a manner that still preserves its structure and sequence. In the end, you'll have enough DNA to see with the unaided eye, and you'll be able to spool it to demonstrate its strand-like structure. Read more
BioChem_p001
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Time Required Average (6-10 days)
Material Availability Readily available
Cost Low ($20 - $50)
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