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Science Fair Project Idea
Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
MicroBio_p019
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability This science project requires access to some laboratory equipment, such as a 37°C incubator, as well as some specialty reagents, which can be ordered online. See the Materials and Equipment list for more details.
Cost High ($100 - $150)
Safety This science project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed, see the for more details. To maintain a sterile environment, you will be working near a lighted Bunsen burner. Keep all flammables, including hair and clothing, away from the flame.
Science Fair Project Idea
This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more
MicroBio_p013
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Time Required Long (2-4 weeks)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Science Fair Project Idea
Have you ever had to sort a jumble of objects into piles, based on their type? Maybe laundry, or a big load of dishes, or while organizing the garage or a closet? Scientists have to do something similar when they want to study or isolate just a single type of protein. For example, a botanist might discover an exotic plant that is poisonous when eaten, but that also has great antibiotic properties. To help develop a new antibiotic for human use, he or she would have to separate the different… Read more
BioChem_p035
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Time Required Average (6-10 days)
Prerequisites Familiarity with how to use a micropipette is needed.
Material Availability This science fair project requires specialty items, including the Bio-Rad and a sample of green fluorescent protein. See the Materials and Equipment list for details. It also requires a number of common molecular biology items, such as pipettes, micropipettes and tips, and a UV light—likely obtainable from your school laboratory.
Cost Very High (over $150)
Safety Adult supervision is recommended. Follow all safety instructions that come with the Bio-Rad kit(s).
Science Fair Project Idea
The rates of some chemical reactions can actually be increased by adding light. Light sometimes interacts with one or more of the chemicals and provides an "energy boost" that dramatically speeds up a normally slow reaction. In this photochemistry science project, you will experiment with the effect of light on a chemical reaction. The reaction converts iodine, which forms a dark-orange solution, to iodide, which is colorless! Read more
Chem_p095
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Time Required Average (6-10 days)
Prerequisites An introductory chemistry class.
Material Availability You will need basic lab equipment, which can be ordered online. See the Materials and Equipment list for details.
Cost Average ($50 - $100)
Safety Gloves and safety goggles are required. Oxalic acid is toxic and an irritant. Avoid breathing oxalic acid dust and avoid contact with skin. Ammonia is an irritant. Iodine is also an irritant and stains clothes and skin. Adult supervision is required.
Science Fair Project Idea
In this project, you'll learn how to isolate DNA from onion cells, separating it from other cellular components in a manner that still preserves its structure and sequence. In the end, you'll have enough DNA to see with the unaided eye, and you'll be able to spool it to demonstrate its strand-like structure. Read more
BioChem_p001
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety Use caution when handling ethanol because it is very flammable. Adult supervision is recommended for using the stove and a food processor or blender.
Science Fair Project Idea
Are you interested in the technical and ethical aspects of genetic screening, forensic science, and DNA fingerprinting? Scientists use different forms of a gene, called alleles, to differentiate between two fingerprints. One such sequence used in human DNA fingerprinting is the Alu repeat (a 300 base pair repetitive sequence of DNA) on chromosome 16. During evolutionary time, up to 1 million copies of the Alu repeat have become randomly inserted throughout the human genome. Within a specific… Read more
BioChem_p022
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Time Required Very Long (1+ months)
Prerequisites Access to a research laboratory with PCR equipment is required for this project.
Material Availability available for purchase online from Bio-Rad. See for details on how to purchase kits from Bio-Rad.
Science Fair Project Idea
If you want to get your friend's attention at a crowded sporting event with lots of people cheering, you need to shout. If you're trying to do the same thing in a quiet library, a whisper works. The detection limit for each of our senses depends on the amount of "background" stimulation that is already present. This project uses an LED control circuit to investigate detection of changes in light levels. Read more
Elec_p039
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Time Required Short (2-5 days)
Prerequisites Understanding of Ohm's Law and an understanding of logarithms. Note: the biggest expense is a powered, solderless breadboard, which can be used for future explorations in electronics.
Material Availability Specialty items
Cost Very High (over $150)
Safety No issues
Science Fair Project Idea
Water is an interesting thing. We drink it, swim in it, and wash ourselves with it. We can get energy from water by damming it and sending it through a turbine. But did you know that we can use the natural electrical charges present in water and a Kelvin electrostatic generator to create sparks? You can even use a Kelvin electrostatic generator to temporarily light a bulb! Now that is one bright idea! Read more
Elec_p069
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Time Required Average (6-10 days)
Prerequisites None
Material Availability You will need to visit your local hardware store to purchase plumbing items to build the Kelvin electrostatic generator. You will also need a hand saw, a drill, a heat gun, a digital scale, a fan, and a dehumidifier. See the Materials and Equipment list for details. Cost of the project may be lower depending on what tools you already have available.
Cost High ($100 - $150)
Safety Parts of the Kelvin electrostatic generator require use of a hand saw and a drill. Wear safety goggles when using power tools. Adult supervision is required.
Science Fair Project Idea
It is fun to shake up a snow globe and watch the "snow" slowly fall. You can imagine that if the snow fell down very quickly it would be disappointing. But there are times when scientists in a laboratory want this to happen. Scientists use samples that have liquid mixed with small, solid pieces (like the inside of a snow globe), and they need all of the solid pieces in a clump, separated from the liquid. Instead of waiting for the pieces to slowly fall out of the liquid, scientists speed up… Read more
BioChem_p041
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Time Required Short (2-5 days)
Prerequisites None
Material Availability You will need to purchase the centrifuge tubes online. See the Materials and Equipment section for details.
Cost Average ($40 - $80)
Safety No issues
Science Fair Project Idea
Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more
BioChem_p034
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Time Required Average (6-10 days)
Prerequisites Prior to starting this science fair project, you should either know how to use a spectrophotometer, or have access to someone who can show you how to use it.
Material Availability This science fair project requires access to laboratory equipment and supplies, including a spectrophotometer; see the Materials and Equipment section for more details. Access to a dairy is also needed for the main project, but the Variations section, below, lists options that are not dependent on dairy access.
Cost Very High (over $150)
Safety Adult supervision is recommended when using laboratory equipment.
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