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Science Fair Project Idea
Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more
BioChem_p036
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability You will need to order a UV-sensitive yeast kit online. See the Materials and Equipment list for details. Note: You might have to have the yeast delivered to a school if the company does not deliver to residential addresses.
Cost High ($100 - $150)
Safety Pouring hot agar plates should be done with caution.
Science Fair Project Idea
Can you lift a car? No? You say you are not strong enough? True, our bodies are not built to lift heavy loads like cars. Fortunately, our brains are smart enough to harness the power of fluids, like water and oil, to create hydraulic lifts. By pushing a button on a hydraulic lift, a mechanic can easily raise a car with one finger. Lifts can also be used to raise lots of other heavy loads - even such massive things as steel girders to construct a skyscraper! In this mechanical engineering… Read more
ApMech_p048
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability Syringes, which are needed for this project, can be ordered online. See the Materials and Equipment list for details.
Cost Average ($50 - $100)
Safety Since minor injury is possible, use caution when using a tool such as a saw. Be sure to wear safety goggles when using tools. Use epoxy in a well-ventilated area and follow all of the safety recommendations on the package. Adult supervision is required.
Science Fair Project Idea
Electronic devices can be designed to detect dangerous fumes or other hazards, such as smoke or carbon monoxide. In this electronics project, you will build another potentially life-saving detector—a radon detector. Radon gas is radioactive and can pose a hazard to your health if you live in an area where it leaks from the ground. In this electronics science project, you will learn how to collect radon with an ordinary dusting cloth mounted on the intake of a fan, and then measure its… Read more
Elec_p064
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Time Required Very Long (1+ months)
Prerequisites Since the goal of this science project is to measure radon gas, you should have access to an area that has previously tested positive for radon with a commercial radon detection system. See the Experimental Procedure section for details. This is an advanced science project that will require creative problem solving on your part.
Material Availability While most of the parts for this science project are readily available, you might need to be creative about finding or making some of the parts.
Cost High ($100 - $150)
Safety Wear safety goggles when drilling and soldering. Adult supervision is recommended.
Science Fair Project Idea
What color is grape soda? If you pour it into a clear glass you can easily see it is purple, but that is usually not its natural color. Manufacturers add red and blue dye to the soda. The dyes mix together and you get purple soda. What if you wanted to un-mix the dyes, could you? Yes! In a chemistry laboratory, using a technique called column chromatography, you could separate the two dyes again. But what about at home, can you use low-tech supplies to do the same thing? In this science… Read more
BioChem_p045
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Syringes (without needles) and Space Sand need to be specially ordered. See the Materials and Equipment list for details.
Cost Low ($20 - $50)
Safety Use caution and follow all safety warnings when handling and using the 70% isopropyl alcohol. The alcohol is highly flammable. Do not swallow, and wear safety goggles to avoid any contact with eyes.
Science Fair Project Idea
Are you interested in the technical and ethical aspects of genetic screening, forensic science, and DNA fingerprinting? Scientists use different forms of a gene, called alleles, to differentiate between two fingerprints. One such sequence used in human DNA fingerprinting is the Alu repeat (a 300 base pair repetitive sequence of DNA) on chromosome 16. During evolutionary time, up to 1 million copies of the Alu repeat have become randomly inserted throughout the human genome. Within a specific… Read more
BioChem_p022
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Time Required Very Long (1+ months)
Prerequisites Access to a research laboratory with PCR equipment is required for this project.
Material Availability available for purchase online from Bio-Rad. See for details on how to purchase kits from Bio-Rad.
Science Fair Project Idea
Did you know that your body needs a certain amount of iron in order to stay healthy? Iron can be found in much of what you consume each day. Almond meal—frequently used in cookies—is just one example of an iron-rich food. However, only a small fraction of the iron in food gets absorbed by the body, partially because the body can only absorb dissolved iron. In this project, you will study whether the acidic environment in your stomach helps dissolve iron. You will use a color-based… Read more
HumBio_p043
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Time Required Average (6-10 days)
Prerequisites None
Material Availability This science project requires an iron test kit, available from . The Time Required estimate includes time for obtaining materials. Actual experimental time is only a few hours.
Cost Average ($40 - $80)
Safety The chemicals in the test kit could cause irritation if not handled properly. Be sure to wear gloves, safety goggles, and work in a well-ventilated area. Adult supervision is recommended. The small amount of sulfites contained in the iron indicator tablets may cause an allergic reaction in people who have asthma.
Science Fair Project Idea
Is it possible to manipulate bacteria to become protein production factories? Can diabetics control blood glucose with insulin produced by bacteria? How cool would it be to take advantage of these microorganism's sophisticated makeup, short doubling times and cheap growth media to mass produce medically and commercially useful proteins? All of these are possible with a few simple genetic manipulations. By the end of this project you would know the basic foundation on which many… Read more
BioChem_p013
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipets all helpful.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Requires adult supervision in a laboratory facility. For ISEF-affiliated fairs, this project will require approval.
Science Fair Project Idea
Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
MicroBio_p019
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability This science project requires access to some laboratory equipment, such as a 37°C incubator, as well as some specialty reagents, which can be ordered online. See the Materials and Equipment list for more details.
Cost High ($100 - $150)
Safety This science project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed, see the for more details. To maintain a sterile environment, you will be working near a lighted Bunsen burner. Keep all flammables, including hair and clothing, away from the flame.
Science Fair Project Idea
The Pilobolus fungus has an interesting way of making sure the next generation has a good start on life. At high speed, the fungus shoots a sac that contains spores toward a light source. Why toward a light source? Because that is where it is most likely to find an open area with grass. Once the spore is placed on grass, it is eaten by a cow or a horse, which is a critical step in its life cycle. The spore passes through the animal's digestive track and ends up in a pile of manure. For a fungal… Read more
MicroBio_p027
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Time Required Long (2-4 weeks)
Prerequisites Note: Pilobolus is grown on rabbit dung embedded in plain agar. A strong stomach is a prerequisite for working with this culture.
Material Availability You will need to order a Pilobolus culture kit online. See the Materials and Equipment list for details. You should work with your teacher to have the kit delivered to your teacher at school, since there are restrictions on sending it to a residential address.
Cost Average ($50 - $100)
Safety No issues
Science Fair Project Idea
Look out! When you walk on the grass, you are squishing millions of micro-invertebrates! Just kidding, these animals are too small to squish. Learn how to catch them by making a Berlese funnel in this fun project that will teach you about soil. Read more
EnvSci_p042
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- Less Details
Time Required Short (2-5 days)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
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