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Science Fair Project Idea
thumbnail Nut clusters, chocolate-dipped candies, and chocolate-dipped strawberries are just some of the delicious goodies that have a thin, rich layer of chocolate wrapped around them. But how do pastry and candy chefs make these delectable treats? The first step is to melt and temper chocolate. Tempering is a process in which the cocoa butter in chocolate is hardened into a specific crystalline pattern. When the cocoa butter molecules are in this pattern, the chocolate is shiny and breaks with a sharp… Read more
FoodSci_p038
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety Minor injury possible. Use caution when using a stovetop. Hot chocolate can burn. Use care when working with hot chocolate. Adult supervision recommended.
Science Fair Project Idea
thumbnail Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science project,… Read more
BioMed_p011
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Time Required Short (2-5 days)
Prerequisites Basic understanding of what viruses, drugs, genes, and proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
Remember going to the doctor and getting vaccine shots? It is no fun getting poked with a needle, but fortunately, a vaccine gives you protection against a serious illness for years to come. But what about the flu vaccine? How come there is a new one every year? This science fair project will show you why. Read more
Genom_p003
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Time Required Average (6-10 days)
Prerequisites Excellent computer skills. Basic understanding of immunology and protein sequences or willingness to learn about these topics.
Material Availability None required
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Have you ever enjoyed eating a tasty sweet potato? They can be served as yummy mashed sweet potatoes with melted butter, turned into golden-brown sweet potato fries, or prepared in many other scrumptious ways. Did you know that you can make a sweet potato grow into a sweet potato plant, and grow several sweet potatoes this way? In this science project, you will grow your own sweet potato plants and investigate what part of the sweet potatoes is needed to grow the plants. Read more
PlantBio_p017
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Time Required Very Long (1+ months)
Prerequisites None
Material Availability Readily available
Cost Very Low (under $20)
Safety Parental assistance is required for using the knife.
Science Fair Project Idea
thumbnail Have you ever wished you could talk to an astronaut on board the International Space Station? You're probably thinking "yeah, like NASA would ever let you do that!" Actually, they will! The International Space Station (ISS) is equipped with its own HAM radio station. The allows astronauts, cosmonauts, and space mission specialists from different nations who are on board the space station to talk to people back home on Earth. Anyone with an amateur radio license is welcome to try… Read more
Phys_p080
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Time Required Short (2-5 days)
Prerequisites You'll need to an amateur radio license (or work with someone who has one) to complete this project. Details on getting a license can be found at the [# Link Name="Phys_p080.2" Value="HtmlAnchor" #] website.
Material Availability This project requires access to HAM radio equipment and a amateur radio license.
Cost Very High (over $150)
Safety No issues
Science Fair Project Idea
How a biological system functions is a consequence of the 3-D structures of biological macromolecules like proteins and protein complexes. Proteins can be categorized into different protein families based upon sequence, structure, and function. Typically, proteins in the same family have similar biochemical functions. You can investigate the structure of a protein by using protein databases (Entrez Protein, SwissProt, PDB) and 3-D computational models. You can compare the structures of… Read more
BioChem_p021
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Time Required Very Long (1+ months)
Prerequisites Advanced biology course, or willingness to read up on such topics extensively.
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
thumbnail Believe it or not, scientists were recently able to recover tissue from a 68-million-year-old Tyrannosaurus rex fossil! Not only were they able to purify non-mineralized tissue, but they also succeeded in obtaining partial sequence information for protein molecules in the T. rex tissue. In this genomics science fair project, you will use the T. rex's protein sequence to search sequence databases for the its closest living relatives. Read more
Genom_p018
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Time Required Average (6-10 days)
Prerequisites None
Material Availability Readily available
Cost Low ($20 - $50)
Safety No issues
Science Fair Project Idea
thumbnail Native plants are important for both ecological and medicinal reasons. However, most native plants are not very well studied. One way to know more about these plants is to understand which other species of plants they are most closely related to. In this science project you will sequence part of the chloroplast genome from a native plant and use this information to determine its evolutionary relationship to other species of plants. If the plant you chose has not been sequenced before, you can… Read more
Genom_p012
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Time Required Long (2-4 weeks)
Prerequisites High school biology class; familiarity with using the PCR machine and gel electrophoresis equipment, and/or using the equipment with a mentor.
Material Availability You will need specialized pieces of equipment, including a PCR machine (thermocycler) and a gel electrophoresis apparatus. If your school does not have this equipment you might want to seek out a mentor at a junior college, university, or biotechnology company. If you have the resources you can do the DNA sequencing yourself, otherwise you can send the samples to Dr. Baysdorfer at California State University, East Bay, see Experimental Procedure for more details.
Cost High ($100 - $150)
Safety This project uses ethidium bromide, which is a carcinogen. Always wear gloves and safety goggles when handling. Dispose of the ethidium bromide according to your school or institute's hazardous waste protocols. If you have concerns, ask your teacher or mentor for advice.
Science Fair Project Idea
Unlocking the three-dimensional structure of a protein is crucial to help scientists understand how it functions in our bodies and how it can cause devastating diseases if it becomes disrupted or interacts in the wrong way. However, figuring out the structure of a protein in three-dimensional space can be very challenging. Proteins are the functional units of our cells, and every protein is made up of a long chain of amino acids. Amino acids come in different shapes and sizes, and they have… Read more
BioMed_p008
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Time Required Long (2-4 weeks)
Prerequisites Understanding of what proteins are.
Material Availability Readily available
Cost Very Low (under $20)
Safety No issues
Science Fair Project Idea
The DNA in our cells contains our "blueprints," but it's the proteins in our cells that do most of the work. The Human Genome Project has allowed us to start reading the blueprints, but we still don't understand what most of the proteins do. This is a fairly advanced project that explores ways of identifying the function of unknown proteins. Read more
Genom_p002
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Time Required Long (2-4 weeks)
Prerequisites High School Biology, excellent computer skills
Material Availability None required
Cost Very Low (under $20)
Safety No issues
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