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Science Fair Project Idea
Is it possible to manipulate bacteria to become protein production factories? Can diabetics control blood glucose with insulin produced by bacteria? How cool would it be to take advantage of these microorganism's sophisticated makeup, short doubling times and cheap growth media to mass produce medically and commercially useful proteins? All of these are possible with a few simple genetic manipulations. By the end of this project you would know the basic foundation on which many… Read more
BioChem_p013
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipets all helpful.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Requires adult supervision in a laboratory facility. For ISEF-affiliated fairs, this project will require [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC" #] approval.
Science Fair Project Idea
thumbnail Do you know what is living in your backyard? How about at the playground, or in your compost pile? Nematodes, also called roundworms, are the most abundant animal on Earth and they might be living in any of these places. In this science project you'll isolate nematodes from several soil samples to discover the best nematode habitats. Read more
Zoo_p045
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability The E. coli culture and the agar plates are specialty items. They can be ordered online (see Materials and Equipment for more details), but you will need to plan ahead.
Cost Low ($20 - $50)
Safety This science project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed.
Science Fair Project Idea
Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more
BioChem_p036
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability You will need to order a UV-sensitive yeast kit online. See the Materials and Equipment list for details. Note: You might have to have the yeast delivered to a school if the company does not deliver to residential addresses.
Cost High ($100 - $150)
Safety Pouring hot agar plates should be done with caution.
Science Fair Project Idea
thumbnail Have you ever noticed that most yogurt containers say they contain "live cultures"? What does that mean? The label is suggesting that the yogurt has living bacteria in it! While some types of bacteria can make you sick, some are actually important to keep you healthy. But individual bacteria are so tiny that you cannot see one with the naked eye, so how can you tell if bacteria are really living in your yogurt? In this science fair project, you will investigate whether yogurt actually… Read more
FoodSci_p072
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability You will need to special order the agar plates. See the Materials and Equipment list for details.
Cost Average ($40 - $80)
Safety The bacteria in the yogurt is not harmful; however, it is possible for other bacteria to grow on the agar plates. For that reason, make sure to follow all the safety guidelines in the Experimental Procedure. Be sure to dispose properly any plates with bacteria when the experiment is over. Adult help is required to light a candle.
Science Fair Project Idea
thumbnail Have you ever thought about how fortunate you are to have safe and clean water coming out of your faucet? Many people in undeveloped nations don't have this luxury. But does that mean they can't have clean water at all? Is there an inexpensive way they could use to make their own clean water? In this microbiology science fair project, you will investigate whether or not sunlight can disinfect contaminated water. Read more
MicroBio_p025
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Time Required Long (2-4 weeks)
Prerequisites You should have access to a local stream or creek.
Material Availability Specialty items are required. You will need to purchase tryptic soy agar plates, droppers, and glass rods for streaking. See the Materials and Equipment section, below, for more details.
Cost Average ($50 - $100)
Safety This science fair project deals with potentially dangerous pathogens. Wear gloves when conducting the experiment. Read and follow the instructions in the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #]. Do not drink any of the water that results from the SODIS process. See the Experimental Procedure for more information. You should always exercise caution when obtaining a water sample from a creek or a stream.
Science Fair Project Idea
thumbnail Ultraviolet light can damage DNA molecules. If a cell's DNA repair mechanisms can't keep up with the damage, mutations are the result. As harmful mutations accumulate, the cell eventually dies. How much ultraviolet light is too much for a bacterial cell? Read more
MicroBio_p017
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Time Required Average (6-10 days)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Adult supervision required. Read and follow the safety note below on ultraviolet light. Follow standard precautions for handling bacterial cultures.
Science Fair Project Idea
thumbnail In this biology science fair project, you will observe how the Physarum polycephalum (P. polycephalum) organism responds to various amounts of glucose. P. polycephalum is easy to grow in a petri dish and responds in complex ways to its environment. Will it grow toward the chemical as it looks for a meal, or will it flee, trying to avoid further contact? Try this science fair project to learn more about chemotaxis in the fascinating Physarum polycephalum. Read more
MicroBio_p028
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Time Required Long (2-4 weeks)
Prerequisites An introductory course in chemistry would be useful.
Material Availability You will need to order the "Chemotaxis in Physarum" kit online; see the Materials and Equipment list for details. This item may have to be ordered by your teacher.
Cost Average ($50 - $100)
Safety Be careful working with sharp blades. Adult supervision is recommended.
Science Fair Project Idea
Microbes are everywhere in our environment, but for the most part they escape our notice. This project shows you how to safely culture and study common bacteria from your everyday surroundings. Read more
MicroBio_p007
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Time Required Long (2-4 weeks)
Material Availability Agar plates must be specially ordered
Cost Low ($20 - $50)
Safety Must follow general safety precautions for handling microorganisms
Science Fair Project Idea
thumbnail Crown gall is a plant disease caused by the soil bacterium Agrobacterium tumefaciens. This project uses tomato plants to investigate whether garlic extract can prevent crown gall infection. Read more
MicroBio_p024
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Time Required Long (2-4 weeks)
Prerequisites You will need a plant with an existing crown gall infection as a source of bacteria for this project.
Material Availability Readily available
Cost Low ($20 - $50)
Safety Use caution when cutting with sharp knife or razor blade.
Science Fair Project Idea
thumbnail Can a simple organism that lives off of dead trees and that grows as a mass of protoplasm actually have intelligence? The goal of this science fair project is to test the ability of the slime mold Physarum polycephalum to solve the problem of finding the shortest path through a maze. Read more
Zoo_p060
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability You will need a Physarum polycephalum culture kit. See the Materials and Equipment list for details.
Cost Average ($50 - $100)
Safety Use caution when working with sharp blades and when working with hot solutions.
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