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Project Idea
thumbnail Germs are everywhere! We try and clean our home with disinfectants, but do we really get rid of all the germs? Find out with this "hands-on" experiment. Read more
MicroBio_p012
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Specialty items
Cost Average ($40 - $80)
Safety Must follow general safety precautions for handling microorganisms
Project Idea
thumbnail This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more
MicroBio_p013
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Time Required Long (2-4 weeks)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Project Idea
thumbnail Have you ever noticed that most yogurt containers say they contain "live cultures"? What does that mean? The label is suggesting that the yogurt has living bacteria in it! While some types of bacteria can make you sick, some are actually important to keep you healthy. But individual bacteria are so tiny that you cannot see one with the naked eye, so how can you tell if bacteria are really living in your yogurt? In this science fair project, you will investigate whether yogurt actually… Read more
FoodSci_p072
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability You will need to special order the agar plates. See the Materials and Equipment list for details.
Cost Average ($40 - $80)
Safety The bacteria in the yogurt is not harmful; however, it is possible for other bacteria to grow on the agar plates. For that reason, make sure to follow all the safety guidelines in the Experimental Procedure. Be sure to dispose properly any plates with bacteria when the experiment is over. Adult help is required to light a candle.
Project Idea
Did you know that a scientific study has shown that chewing Big Red Gum reduces mouth microbes? (ScienceDaily contributors, 2004) The cinnamon oil in the gum is a natural defense against mouth bacteria that cause tooth decay and bad breath. Conduct an experiment to compare products with cinnamon essence in gum, candy, toothpaste, and mouthwash to see if they can decrease mouth germs. Do a before and after swab of the mouth with a Q-tip. Which treatments work the best? Can you find another… Read more
MicroBio_p023
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Time Required Long (2-4 weeks)
Prerequisites A basic knowledge of how to work with bacteria is needed to complete this science fair project. Consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" HtmlText="Microbiology Techniques and Troubleshooting" #] guide for information on how to conduct microbiology experiments.
Material Availability Specialty items, like the media to grow bacteria on, can be ordered from [# ProjectGuide Name="Advanced.ApprovedSuppliers" Value="HtmlAnchor" HtmlText="online vendors" #] such as [# Link Name="Advanced.ApprovedSuppliers.2" Value="HtmlAnchor" HtmlText="Carolina Biological Supply Company" #].
Cost Average ($50 - $100)
Safety Use sterile technique. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary. Adult supervision is recommended.
Project Idea
thumbnail Have you heard that garlic powder is supposed to inhibit the growth of bacteria? Which do you think would make a better disinfectant: a solution of garlic powder or a solution of bleach? This project shows you a straightforward way to compare the effectiveness of different disinfectants (or other antimicrobial agents), by measuring zones of inhibition on a culture plate. Read more
MicroBio_p014
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Time Required Average (6-10 days)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Project Idea
thumbnail Have you ever thought about how fortunate you are to have safe and clean water coming out of your faucet? Many people in undeveloped nations don't have this luxury. But does that mean they can't have clean water at all? Is there an inexpensive way they could use to make their own clean water? In this microbiology science fair project, you will investigate whether or not sunlight can disinfect contaminated water. Read more
MicroBio_p025
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Time Required Long (2-4 weeks)
Prerequisites You should have access to a local stream or creek.
Material Availability Specialty items are required. You will need to purchase tryptic soy agar plates, droppers, and glass rods for streaking. See the Materials and Equipment section, below, for more details.
Cost Average ($50 - $100)
Safety This science fair project deals with potentially dangerous pathogens. Wear gloves when conducting the experiment. Read and follow the instructions in the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #]. Do not drink any of the water that results from the SODIS process. See the Experimental Procedure for more information. You should always exercise caution when obtaining a water sample from a creek or a stream.
Project Idea
Antibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different… Read more
MicroBio_p021
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Time Required Long (2-4 weeks)
Prerequisites This project requires access to bacteria and antibiotics in a laboratory setting. A basic knowledge of how to work with bacteria is needed to complete this science fair project. Consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" HtmlText="Microbiology Techniques and Troubleshooting" #] guide for information on how to conduct microbiology experiments.
Material Availability Specialty items, like bacteria and the media to grow them on, can be ordered from [# ProjectGuide Name="Advanced.ApprovedSuppliers" Value="HtmlAnchor" HtmlText="online vendors" #] such as [# Link Name="Advanced.ApprovedSuppliers.2" Value="HtmlAnchor" HtmlText="Carolina Biological Supply Company" #].
Cost High ($100 - $150)
Safety Requires adult supervision in a laboratory setting. Use sterile technique. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary.
Project Idea
Some proteins are soluble in aqueous solutions and some are not. Insoluble proteins can be a problem because the proteins can form large aggregates in solution which are difficult to purify, crystallize, and use in experiments. Compare the amino acid sequence and 3-D structures of some soluble and insoluble proteins (Berman, 2000). Is the structure polar or non-polar, and how might this affect solubility? How do detergents make an insoluble protein more soluble? Investigate how this… Read more
BioChem_p018
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Time Required Long (2-4 weeks)
Prerequisites Basic introduction to chemistry
Material Availability A computer with Internet access is necessary for this project.
Cost Very Low (under $20)
Safety No issues
Project Idea
thumbnail Have you ever wondered if a piece of jewelry is real gold or if it's just some ordinary metal alloy? It turns out that some metals have a unique property; even in small amounts, they can be toxic to some organisms, including algae, molds, fungi, and bacteria, although it often takes many hours to see an effect. Can this phenomena, called the oligodynamic effect be used to tell whether or not the gold or silver in a piece of jewelry is real? Do bacteria react differently to pure, plated, and… Read more
MicroBio_p026
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability This science fair project requires access to some laboratory equipment, such as a 37°C incubator, a Bunsen burner, as well as some specialty reagents, which can be ordered online. It also requires several pieces of jewelry, including at least one 14-karat gold piece. See the Materials and Equipment list for more details.
Cost Average ($50 - $100)
Safety This science fair project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed. See the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] for more details. Projects using bacteria may require pre-approval from your science fair's [# Link Name="MicroBio_p026.1" Value="HtmlAnchor" #]. To maintain a sterile environment, you will be working near a lighted Bunsen burner. Keep all flammables, including hair and clothing, away from the flame.
Project Idea
thumbnail Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
MicroBio_p019
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability This science project requires access to some laboratory equipment, such as a 37°C incubator, as well as some specialty reagents, which can be ordered online. See the Materials and Equipment list for more details.
Cost High ($100 - $150)
Safety This science project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed, see the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] for more details. To maintain a sterile environment, you will be working near a lighted Bunsen burner. Keep all flammables, including hair and clothing, away from the flame.
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