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Others Like “Natural Antimicrobial Agents”

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Science Fair Project Idea
Antibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different… Read more
MicroBio_p021
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Time Required Long (2-4 weeks)
Prerequisites This project requires access to bacteria and antibiotics in a laboratory setting. A basic knowledge of how to work with bacteria is needed to complete this science fair project. Consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" HtmlText="Microbiology Techniques and Troubleshooting" #] guide for information on how to conduct microbiology experiments.
Material Availability Specialty items, like bacteria and the media to grow them on, can be ordered from [# ProjectGuide Name="Advanced.ApprovedSuppliers" Value="HtmlAnchor" HtmlText="online vendors" #] such as [# Link Name="Advanced.ApprovedSuppliers.2" Value="HtmlAnchor" HtmlText="Carolina Biological Supply Company" #].
Cost High ($100 - $150)
Safety Requires adult supervision in a laboratory setting. Use sterile technique. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary.
Science Fair Project Idea
thumbnail Have you heard that garlic powder is supposed to inhibit the growth of bacteria? Which do you think would make a better disinfectant: a solution of garlic powder or a solution of bleach? This project shows you a straightforward way to compare the effectiveness of different disinfectants (or other antimicrobial agents), by measuring zones of inhibition on a culture plate. Read more
MicroBio_p014
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Time Required Average (6-10 days)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Science Fair Project Idea
thumbnail Crown gall is a plant disease caused by the soil bacterium Agrobacterium tumefaciens. This project uses tomato plants to investigate whether garlic extract can prevent crown gall infection. Read more
MicroBio_p024
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Time Required Long (2-4 weeks)
Prerequisites You will need a plant with an existing crown gall infection as a source of bacteria for this project.
Material Availability Readily available
Cost Low ($20 - $50)
Safety Use caution when cutting with sharp knife or razor blade.
Science Fair Project Idea
Did you know that a scientific study has shown that chewing Big Red Gum reduces mouth microbes? (ScienceDaily contributors, 2004) The cinnamon oil in the gum is a natural defense against mouth bacteria that cause tooth decay and bad breath. Conduct an experiment to compare products with cinnamon essence in gum, candy, toothpaste, and mouthwash to see if they can decrease mouth germs. Do a before and after swab of the mouth with a Q-tip. Which treatments work the best? Can you find another… Read more
MicroBio_p023
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Time Required Long (2-4 weeks)
Prerequisites A basic knowledge of how to work with bacteria is needed to complete this science fair project. Consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" HtmlText="Microbiology Techniques and Troubleshooting" #] guide for information on how to conduct microbiology experiments.
Material Availability Specialty items, like the media to grow bacteria on, can be ordered from [# ProjectGuide Name="Advanced.ApprovedSuppliers" Value="HtmlAnchor" HtmlText="online vendors" #] such as [# Link Name="Advanced.ApprovedSuppliers.2" Value="HtmlAnchor" HtmlText="Carolina Biological Supply Company" #].
Cost Average ($50 - $100)
Safety Use sterile technique. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary. Adult supervision is recommended.
Science Fair Project Idea
thumbnail Most people are not aware that the soil around them is a battle scene. The combatants are very small—bacteria on one side and bacteriophage on the other. The bacteriophage (or phage for short) try to pierce the outer coats of the bacteria and inject them with phage DNA. If successful, the DNA will take over the inner machinery of the bacterial cells and force them to make many copies of the phage. After the copies are made, the bacterial cells break apart, releasing new phage that start… Read more
MicroBio_p029
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Time Required Long (2-4 weeks)
Prerequisites This is an advanced science project that requires access to a laboratory with a water bath and 37°C incubator. The kit you will use has enough supplies to perform the procedure one time. To repeat the procedure, you should order additional supplies (listed in the Materials and Equipment section), or make your own media and agar plates. Working with a science teacher or other mentor who is familiar with growing bacteria and titering phage would be helpful.
Material Availability You will need to order the bacteria, the phage, and the supplies from an online science supply store. See the Materials and Equipment list for details.
Cost High ($100 - $150)
Safety The bacteria (E. coli B) and the phage (T4r) are not dangerous, but you should follow common-sense safety guidelines and wear gloves and safety goggles when working in the lab. Adult supervision is recommended.
Science Fair Project Idea
Disinfectants are products that kill harmful bacteria that inhabit surfaces. Disinfectants can be in household and personal cleaning products. Which products work best? Compare different household cleaning products, like bleach or Lysol, to see which ones kill the most bacteria. Compare different brands of antibacterial hand soap or dish soap to see which brand is the most effective. How do hand sanitizers work? Compare rub-on hand sanitizers to see if they work better than alcohol, or compare… Read more
MicroBio_p020
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Time Required Average (6-10 days)
Prerequisites Knowledge about growing and testing bacteria
Material Availability Specialty items, like bacteria and the media to grow them on, can be ordered from [# ProjectGuide Name="Advanced.ApprovedSuppliers" Value="HtmlAnchor" HtmlText="online vendors" #] such as [# Link Name="Advanced.ApprovedSuppliers.2" Value="HtmlAnchor" HtmlText="Carolina Biological Supply Company" #].
Cost Low ($20 - $50)
Safety Follow all safety warnings printed on the cleaning solutions you are using. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. Adult supervision is recommended. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary.
Science Fair Project Idea
thumbnail This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more
MicroBio_p013
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Time Required Long (2-4 weeks)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Science Fair Project Idea
thumbnail Is it possible to manipulate bacteria to become protein production factories? Can diabetics control blood glucose with insulin produced by bacteria? How cool would it be to take advantage of these microorganism's sophisticated makeup, short doubling times and cheap growth media to mass produce medically and commercially useful proteins? All of these are possible with a few simple genetic manipulations. By the end of this project you would know the basic foundation on which many… Read more
BioChem_p013
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipets all helpful.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Requires adult supervision in a laboratory facility. For ISEF-affiliated fairs, this project will require [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC" #] approval.
Science Fair Project Idea
thumbnail Topsoil is packed with bacteria that generate electricity when placed in a microbial fuel cell (MFC). Because such bacteria-laden soil is found almost everywhere on Earth, microbial fuel cells can make clean, renewable electricity nearly anyplace around the globe. As natural resources are being depleted, scientists' attention has shifted to pursuing alternative energy sources, such as MFCs, even more than before. A microbial fuel cell, also known as a biological fuel cell, is a device that can… Read more
MicroBio_p032
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Time Required Very Long (1+ months)
Prerequisites Previous experience using a voltmeter/multimeter is helpful, but not required. A basic knowledge of how to work with bacteria is also needed to complete this science fair project. Consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" HtmlText="Microbiology Techniques and Troubleshooting" #] guide for information on how to conduct microbiology experiments.
Material Availability A microbial fuel cell and other specialty items are needed. See the Materials tab for more details.
Cost Average ($50 - $100)
Safety Be sure to wear the gloves supplied with the kit when handling the microbial fuel cell’s electrodes (its cathode and anode). The electrodes are made of a conductive material called graphite fiber and should not be placed near electronics or power plugs, or have their fibers dispersed in the air. Use sterile technique when growing the bacteria. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary. Adult supervision is recommended.
Science Fair Project Idea
thumbnail What is cloning and how is it used in the biotechnology industry? How are plasmids constructed for use in a bacterial expression system? You can investigate bacterial expression with the from the Bio-Rad Biotechnology Explorer Program to make bacteria express green fluorescent protein (GFP), as shown in Figure 1, below (see the Science Buddies project, ). With variations to this kit you can test the conditions for pGLO expression under different conditions. You can also combine with… Read more
BioChem_p024
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience is required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipettes are all helpful.
Material Availability In the Summary tab change the Material Availability field to read: This science project requires the purchase of Bio-Rad's [# Link Name="BioChem_p035.6" Value="HtmlAnchor" #]. You will need a teacher's help to order the kit as Bio-Rad only sells directly to schools.
Cost Very High (over $150)
Safety Adult supervision is required in the laboratory facility. Use sterile technique. Read the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] before starting any experiments. [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC approval" #] may be necessary.
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