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Science Fair Project Idea
thumbnail Most people are not aware that the soil around them is a battle scene. The combatants are very small—bacteria on one side and bacteriophage on the other. The bacteriophage (or phage for short) try to pierce the outer coats of the bacteria and inject them with phage DNA. If successful, the DNA will take over the inner machinery of the bacterial cells and force them to make many copies of the phage. After the copies are made, the bacterial cells break apart, releasing new phage that start… Read more
MicroBio_p029
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Time Required Long (2-4 weeks)
Prerequisites This is an advanced science project that requires access to a laboratory with a water bath and 37°C incubator. The kit you will use has enough supplies to perform the procedure one time. To repeat the procedure, you should order additional supplies (listed in the Materials and Equipment section), or make your own media and agar plates. Working with a science teacher or other mentor who is familiar with growing bacteria and titering phage would be helpful.
Material Availability You will need to order the bacteria, the phage, and the supplies from an online science supply store. See the Materials and Equipment list for details.
Cost High ($100 - $150)
Safety The bacteria (E. coli B) and the phage (T4r) are not dangerous, but you should follow common-sense safety guidelines and wear gloves and safety goggles when working in the lab. Adult supervision is recommended.
Science Fair Project Idea
thumbnail Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria. Read more
MicroBio_p019
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability This science project requires access to some laboratory equipment, such as a 37°C incubator, as well as some specialty reagents, which can be ordered online. See the Materials and Equipment list for more details.
Cost High ($100 - $150)
Safety This science project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed, see the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] for more details. To maintain a sterile environment, you will be working near a lighted Bunsen burner. Keep all flammables, including hair and clothing, away from the flame.
Science Fair Project Idea
thumbnail Have you ever heard that nanoparticles can kill bacteria? You may have even seen some consumer products advertise that they contain antibacterial nanoparticles. A nanometer is one billionth of a meter long. Nanoparticles are usually just a few nanometers in diameter — really, really tiny! So how can something that small kill bacteria which are approximately 700 - 1400 nanometers across? Are they really effective? In this science project you will grow some E. coli bacteria and… Read more
MicroBio_p031
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Time Required Average (6-10 days)
Prerequisites You should be familiar with sterile technique and proper handling of bacterial cultures. If you have questions or need a refresher please consult the [# ProjectGuide Name="Advanced.MicrobiologyTechniquesampTroubleshooting" Value="HtmlAnchor" #] guide
Material Availability Some materials need to be special ordered; see the Materials and Equipment list for details
Cost High ($100 - $150)
Safety You must follow general safety precautions for handling microorganisms. See the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] for details.
Science Fair Project Idea
thumbnail Have you ever wondered if a piece of jewelry is real gold or if it's just some ordinary metal alloy? It turns out that some metals have a unique property; even in small amounts, they can be toxic to some organisms, including algae, molds, fungi, and bacteria, although it often takes many hours to see an effect. Can this phenomena, called the oligodynamic effect be used to tell whether or not the gold or silver in a piece of jewelry is real? Do bacteria react differently to pure, plated, and… Read more
MicroBio_p026
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Time Required Long (2-4 weeks)
Prerequisites None
Material Availability This science fair project requires access to some laboratory equipment, such as a 37°C incubator, a Bunsen burner, as well as some specialty reagents, which can be ordered online. It also requires several pieces of jewelry, including at least one 14-karat gold piece. See the Materials and Equipment list for more details.
Cost Average ($50 - $100)
Safety This science fair project involves the use of the bacterium E. coli. Standard microbiology and bacterial safety guidelines should be followed. See the [# ProjectGuide Name="Advanced.MicroorganismsSafetyGuide" Value="HtmlAnchor" HtmlShortTitle="true" #] for more details. Projects using bacteria may require pre-approval from your science fair's [# Link Name="MicroBio_p026.1" Value="HtmlAnchor" #]. To maintain a sterile environment, you will be working near a lighted Bunsen burner. Keep all flammables, including hair and clothing, away from the flame.
Science Fair Project Idea
thumbnail Have you heard that garlic powder is supposed to inhibit the growth of bacteria? Which do you think would make a better disinfectant: a solution of garlic powder or a solution of bleach? This project shows you a straightforward way to compare the effectiveness of different disinfectants (or other antimicrobial agents), by measuring zones of inhibition on a culture plate. Read more
MicroBio_p014
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Time Required Average (6-10 days)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Science Fair Project Idea
Microbes are everywhere in our environment, but for the most part they escape our notice. This project shows you how to safely culture and study common bacteria from your everyday surroundings. Read more
MicroBio_p007
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Time Required Long (2-4 weeks)
Material Availability Agar plates must be specially ordered
Cost Low ($20 - $50)
Safety Must follow general safety precautions for handling microorganisms
Science Fair Project Idea
thumbnail This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more
MicroBio_p013
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Time Required Long (2-4 weeks)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Standard precautions for handling bacterial cultures and bleach.
Science Fair Project Idea
thumbnail Germs are everywhere! We try and clean our home with disinfectants, but do we really get rid of all the germs? Find out with this "hands-on" experiment. Read more
MicroBio_p012
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Time Required Short (2-5 days)
Prerequisites None
Material Availability Specialty items
Cost Average ($40 - $80)
Safety Must follow general [# ProjectIdea Name="MicroBio_p007" Value="HtmlAnchor" HtmlText="safety precautions for handling microorganisms" #]
Science Fair Project Idea
thumbnail Ultraviolet light can damage DNA molecules. If a cell's DNA repair mechanisms can't keep up with the damage, mutations are the result. As harmful mutations accumulate, the cell eventually dies. How much ultraviolet light is too much for a bacterial cell? Read more
MicroBio_p017
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Time Required Average (6-10 days)
Prerequisites To do this project, you will need access to a laboratory with facilities for culturing bacteria. You should be familiar with sterile technique and proper handling of bacterial cultures.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Adult supervision required. Read and follow the safety note below on ultraviolet light. Follow standard precautions for handling bacterial cultures.
Science Fair Project Idea
thumbnail Is it possible to manipulate bacteria to become protein production factories? Can diabetics control blood glucose with insulin produced by bacteria? How cool would it be to take advantage of these microorganism's sophisticated makeup, short doubling times and cheap growth media to mass produce medically and commercially useful proteins? All of these are possible with a few simple genetic manipulations. By the end of this project you would know the basic foundation on which many… Read more
BioChem_p013
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Time Required Average (6-10 days)
Prerequisites Some laboratory experience required: knowledge of sterile technique, working with bacterial cultures, and using automatic pipets all helpful.
Material Availability Specialty items
Cost Average ($50 - $100)
Safety Requires adult supervision in a laboratory facility. For ISEF-affiliated fairs, this project will require [# ProjectGuide Name="Advanced.ScientificReviewCommitteeSRC" Value="HtmlAnchor" HtmlText="SRC" #] approval.
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