Science Buddies: "Ask an Expert"

Would a pill that contains bupropion, mecamylamine, and 18-methoxycoronaridine help people stop smoking by targeting the dopamine pathway and reducing urges to smoke? Please explain why this may or may not work? This is for a prototype that I made of this pill and to test it I need to ask someone who knows a lot about science and medicine. Thanks!!

You made a prototype of this pill with those compounds in it? This does not sound safe, and I would advise against administering it to other people or injecting it yourself.