Science Buddies: "Ask an Expert"

Hi
I am planing to do a science fair project on improving the glucose testing system. I want to come up with a way to test the amount of glucose in the blood without actually taking a sample of the blood. To do this, I need to know what is the absoption spectrum of glucose.
Thank you so much!

You have selected an interesting project. The following web sites will give you and idea of how to approach the problem of measuring glucose.
Lecture Connections: Copper in Brass
spectrum. 6.3. A UV-vis spectrum is produced by the absorption of light. color. 24.5, 24.6 ... a 1.0 M stock solution of glucose is diluted to a total volume ...
icn2.umeche.maine.edu/newnav/NewNavigator/lec/lecbrassv2.html - Cached
[PDF]
Basic UV-Vis Theory, Concepts and Applications
390k - Adobe PDF - View as html
Figure 5 Idealized absorption spectrum ... glucose-6-phosphate to 6-phosphogluconalactone (a reaction catalysed by glucose-6-phosphate ...
http://www.thermo.com/eThermo/CMA/PDFs/ ... _12067.pdf
[PDF]
UV/Vis Light Absorption in Clinical Chemistry
158k - Adobe PDF - View as html
... visible (UV/VIS) absorption spectroscopy has ... The UV/VIS range of the electromagnetic spectrum ... An example of this is the portable glucose monitoring ...
las.perkinelmer.com/.../Articles/ATL_UVVisInClinicalChemistry.pdf
Two Modes of Ligand Binding in Maltose-binding Protein of Escherichia ...
... region below 265 nm of its UV absorption spectrum (R mode, for red) and another ... Shifts from glucose to certain secondary carbon-sources result in ...
www.jbc.org/cgi/content/full/272/28/17605 - 106k

Good luck.

Matthew W. Mulanax

Hi,

You may be interested in the following pages:

http://www.ieee.org/organizations/pubs/ ... frared.htm

http://www.opticsreport.com/content/art ... 002&page=2

http://spiedl.aip.org/getabs/servlet/Ge ... s&gifs=yes

http://www.ingentaconnect.com/content/s ... rmat=print

http://www.mina.ubc.ca/files/Sahba_PTL2_v2_noUL.pdf

http://www.faqs.org/patents/app/20090004682


This paper has a figure and table containing the data I think you are asking for:

http://www.scielo.br/pdf/eq/v31n3/02.pdf

Just a quick scan with Google shows that this is an area of intense interest at the present time. If you can make a significant contribbution it will be a really important achievement!

Good luck!!!!

Barrett Tomlinson

There is actually a noninvasive blood glucose monitoring device that is FDA clear.

http://diabetes.niddk.nih.gov/dm/pubs/g ... /index.htm

This is a neat topic. I am a science journalist and I recently wrote an article about a device, currently under development, that does just what you're describing: http://www.energy.gov/discovery/electro ... escue.html

TroyPercival wrote:There is actually a noninvasive blood glucose monitoring device that is FDA clear.

http://diabetes.niddk.nih.gov/dm/pubs/g ... /index.htm

That is not noninvasive! It still goes in your body!