Science Buddies' twelfth grade science projects are the perfect way for twelfth grade students to have fun exploring science, technology, engineering, and math (STEM). Our twelfth grade projects are written and tested by scientists and are specifically created for use by students in the twelfth grade. Students can choose to follow the science experiment as written or put their own spin on the project.

For a personalized list of science projects, twelfth graders can use the Science Buddies Topic Selection Wizard. The wizard asks students to respond to a series of simple statements and then uses their answers to recommend age-appropriate projects that fit their interests.

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Science Fair Project Idea
When an earthquake occurs, seismic shock waves travel out through the earth from the source of the event. The shock waves travel through the earth or along the Earth's surface, and can be recorded at remote monitoring stations. Some of the waves that travel through the earth are blocked or refracted by the Earth's liquid core, which means that monitoring stations located certain distances from the earthquake do not detect these waves. This creates a "seismic shadow" that you can use to… Read more
Science Fair Project Idea
You have probably seen figures showing how human beings are related to chimpanzees, gorillas, and other primates. In this genomics science fair project, you will use bioinformatics tools to generate your own primate family tree. Read more
Science Fair Project Idea
Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more
Science Fair Project Idea
The Transiting Exoplanet Survey Satellite (TESS) is a space telescope for NASA's Explorers program, designed to search for exoplanets using the transit method in an area 400 times larger than that covered by the Kepler mission. It was launched on April 18, 2018 atop a Falcon 9 rocket. During its two-year primary mission, it was expected to find more than 20,000 transiting exoplanets, compared to about 3,800 exoplanets known when it launched. The first light image from TESS was taken on August… Read more
Science Fair Project Idea
How many websites do you have accounts with that store personal information like your name, email, phone number, or mailing address? If the people running these websites are not careful, hackers could gain unauthorized access to, and even change or delete, your information. They can do this using something called SQL injection, which involves entering malicious code into text fields on a website. In this project you will learn how SQL injection works and figure out how to prevent it. Read more
Science Fair Project Idea
How a biological system functions is a consequence of the 3-D structures of biological macromolecules like proteins and protein complexes. Proteins can be categorized into different protein families based upon sequence, structure, and function. Typically, proteins in the same family have similar biochemical functions. You can investigate the structure of a protein by using protein databases (Entrez Protein, SwissProt, PDB) and 3-D computational models. You can compare the structures of… Read more
Science Fair Project Idea
In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
Science Fair Project Idea
Did you ever wonder about your ancient ancestors? Who they were? Where they came from? In this science project, you will investigate the secrets of your distant past as revealed by your DNA. In order to obtain a sample for DNA analysis, you will scrape a soft swab inside your mouth to collect cheek cells. The cheek cell sample will be sent to a lab for processing, and the results of the analysis will be sent to you. Based on the genetic markers in your DNA, the ancient clan that your… Read more
Science Fair Project Idea
The Sun is the ultimate source of the energy that powers weather systems on Earth. Geomagnetic storms are sun-powered storms in the upper atmosphere, arising from energized particles that are periodically ejected by the Sun. Among other effects, geomagnetic storms can wreak havoc with earth-orbiting satellites, and disrupt satellite communications. The global positioning system (GPS) is a network of 24 earth-orbiting satellites that constantly sends radio signals through the earth's… Read more
Science Fair Project Idea
Can bacteria be altered to produce life-saving insulin for diabetics? Or change color to indicate the presence of a harmful toxin? Yes, it can! Using biotechnology, scientists work daily on problems like these. It starts with selecting a gene you want bacteria to produce and creating a sequence of DNA that has that gene and a promoter that will help express it at the right time and at the right levels. The next hurdle is actually getting this engineered DNA into the bacteria and… Read more
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Free science fair projects.