Science Buddies: "Ask an Expert"

Hi,

A part of my science fair project talks about the Dye-terminator sequencing. And how this mehtod uses nucleotides that have been given a fluorescent colour.
I am wondering how that is done, how do nucleotides get a fluorscent dye?

Thank you. Please reply as soon as possible.

Hi,

Here is an explanation of the sequenceing techniques:

http://en.wikipedia.org/wiki/DNA_sequencing

This book exerpt from Google also describes the technique:

http://books.google.com/books?id=X5yNv0 ... ng&f=false

Here is an explanation in more of an outline form:

http://74.125.155.132/search?q=cache:7W ... clnk&gl=us

I hope this answers the question. This is an important subject of very practical importance in life sciences today. Good luck with the project!

Best regards,

Barrett L. Tomlinson