Antisense oligonucleotides make sense in myotonic dystrophy

Antisense oligonucleotides -- short segments of genetic material designed to target specific areas of a gene or chromosome -- that activated an enzyme to "chew up" toxic RNA could point the way to a treatment for a degenerative muscle disease called myotonic dystrophy, said researchers from Baylor College of Medicine and Isis Pharmaceuticals Inc., in a report in the journal Proceedings of the National Academy of Sciences. Read more