Twelfth Grade Science Projects (201 results)

Science Buddies' twelfth grade science projects are the perfect way for twelfth grade students to have fun exploring science, technology, engineering, and math (STEM). Our twelfth grade projects are written and tested by scientists and are specifically created for use by students in the twelfth grade. Students can choose to follow the science experiment as written or put their own spin on the project.

For a personalized list of science projects, twelfth graders can use the Science Buddies Topic Selection Wizard. The wizard asks students to respond to a series of simple statements and then uses their answers to recommend age-appropriate projects that fit their interests.

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BLAST into the Past to Identify T. Rex's Closest Living Relative

Science Fair Project Idea

Scientific Method

Believe it or not, scientists were recently able to recover tissue from a 68-million-year-old Tyrannosaurus rex fossil! Not only were they able to purify non-mineralized tissue, but they also succeeded in obtaining partial sequence information for protein molecules in the T. rex tissue. In this genomics science fair project, you will use the T. rex's protein sequence to search sequence databases for the its closest living relatives. Read more

Make an Automatic Pill Dispenser

Science Fair Project Idea

Engineering Design Process

Remembering to take medicine at the right time can be hard, especially if you need to take multiple medications at different times of day. It might not be a big deal if you forget to take your daily multivitamin, but for some people, forgetting to take medication at the right time can be dangerous. What if you had a device that could not only set off an alarm at the right time, but also automatically dispense the right pills for you? In this project, you will build an automatic medicine… Read more

Analyzing Impact Craters on Mercury

Science Fair Project Idea

Scientific Method

Have you ever wanted to analyze data from a NASA spacecraft? In this science project you will use data from NASA's MESSENGER mission to measure the diameter and calculate the depth of impact craters on Mercury. You will then analyze that data for relationships between a crater's depth and diameter. This is your chance to perform a science project as a NASA researcher would! Read more

Can AI Diagnose Breast Cancer?

Science Fair Project Idea

Scientific Method

Getting started with machine learning is like unlocking a new world of possibilities, and the best part is that you don't need to be a computer genius to do it! In this project, you will create a K-Nearest Neighbors (KNN) machine learning model that can predict whether a patient has a benign tumor or malignant breast cancer based on the characteristics of the tumor cell nucleus, such as its radius, perimeter, area, and smoothness. Read more

Bioinformatics - The Perfect Marriage of Computer Science & Medicine

Science Fair Project Idea

Scientific Method

Find out the real explanation for why your parents are so weird! Here is a science project that lets you explore the internet to find out why your "DNA blueprint" is so important to health and disease. In this science project, you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more

Crime Scene Chemistry—The Cool Blue Light of Luminol

Science Fair Project Idea

Scientific Method

You may have seen police investigators on TV spraying a crime scene with a liquid that glows blue if there is any blood present. Luminol is the chemical which causes the glowing. In this chemistry science fair project, you will investigate what factors make this interesting molecule "light up." Read more

Use DNA Sequencing to Trace the Blue Whale's Evolutionary Tree

Science Fair Project Idea

Scientific Method

The first land animals took their tentative steps out of the ocean and onto solid ground around 365 million years ago. Over millions of years, these early ancestors developed into tetrapods, including amphibians, reptiles, dinosaurs, birds, and mammals. Then, around 50 million years ago, the reverse process occurred: the mammalian ancestor of today's whales returned to the ocean. In this genomics science fair project, you will use mitochondrial protein sequencing to trace the evolution of… Read more

The Physics of Catapult Projectile Motion

Science Fair Project Idea

Scientific Method

In physics class, you have probably rolled your eyes at some point after being assigned a "projectile motion" homework problem where you use equations to predict how a ball will move through the air. This experiment will show you just how fun that problem can be by using a real catapult to launch a ball and videotaping it as it flies along its path. Then, you will analyze the video and compare it to what the equations predicted. If you have ever wondered if those equations in your physics… Read more

Satellite Collision Detection: A Hands-On Coding Experience

Science Fair Project Idea

Engineering Design Process

Have you ever wondered what would happen if two satellites crashed into each other in space? While space may seem empty, Earth’s orbit is actually crowded with satellites and debris. In this project, you’ll step into the role of a space engineer, using real satellite data to model orbits, track their movement, and predict potential collisions. You’ll explore how gravity and speed affect a satellite’s movement and learn how scientists use simple math and code to prevent… Read more

Predicting Thyroid Cancer Recurrence with Machine Learning

Science Fair Project Idea

Engineering Design Process

For cancer patients, remission–a period when the signs and symptoms of cancer are reduced or disappear–brings immense relief, but there is often a chance of recurrence, or the cancer coming back. Have you ever wondered how doctors can predict if cancer might come back in some patients? Thyroid cancer, a type of cancer affecting the thyroid gland, has a recurrence rate of about 5-30%. Depending on many factors, some patients may have a higher chance of thyroid cancer recurrence than… Read more

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