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hey im doing the protein function (https://www.sciencebuddies.org/mentorin ... l?from=TSW) project, and i understand all the vocabulary fairly well, what i dont understand is how to get these two unkown protiens... any help?
yes i did go to the webpages on the site i provided and i dont understand what im doing...
finding unkown proteins - PLEASE HELP ME
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tinalanese
Getting the protein
Posting for Expert KKurucz
Hi Bayne,
It's a bit unclear from your last post exactly what you are looking for. Are you just looking for information on where to find the proteins to analyze? If so, did you go through some of the references listed in the project:
Choosing a gene/protein to study
http://en.wikipedia.org/wiki/Protein#Functions
Functions
Proteins are involved in practically every function performed by a cell, including regulation of cellular functions such as signal transduction and metabolism. For example, protein catabolism requires only a few enzymes termed proteases.
Mechanisms of protein regulation
Various molecules and ions are able to bind to specific sites on proteins. These sites are called binding sites. They exhibit chemical specificity. The particle that binds is called a ligand. The strength of ligand-protein binding is a property of the binding site known as affinity.
Since proteins are involved in practically every function performed by a cell, the mechanisms for controlling these functions therefore depend on controlling protein activity. Regulation can involve a protein's shape or concentration. Some forms of regulation include:
Allosteric modulation: When the binding of a ligand at one site on a protein affects the binding of ligand at another site.
Covalent modulation: When the covalent modification of a protein affects the binding of a ligand or some other aspect of the protein's function.
Hi Bayne,
It's a bit unclear from your last post exactly what you are looking for. Are you just looking for information on where to find the proteins to analyze? If so, did you go through some of the references listed in the project:
Choosing a gene/protein to study
- Popular science/media stories
Online Mendelian Inheritance in Man: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM
PubMed (searchable database of scientific journal articles) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
- NCBI/Genbank: http://www.ncbi.nlm.nih.gov/ Can access OMIM, BLAST, PubMed from here and search databases of protein and DNA sequences
http://en.wikipedia.org/wiki/Protein#Functions
Functions
Proteins are involved in practically every function performed by a cell, including regulation of cellular functions such as signal transduction and metabolism. For example, protein catabolism requires only a few enzymes termed proteases.
Mechanisms of protein regulation
Various molecules and ions are able to bind to specific sites on proteins. These sites are called binding sites. They exhibit chemical specificity. The particle that binds is called a ligand. The strength of ligand-protein binding is a property of the binding site known as affinity.
Since proteins are involved in practically every function performed by a cell, the mechanisms for controlling these functions therefore depend on controlling protein activity. Regulation can involve a protein's shape or concentration. Some forms of regulation include:
Allosteric modulation: When the binding of a ligand at one site on a protein affects the binding of ligand at another site.
Covalent modulation: When the covalent modification of a protein affects the binding of a ligand or some other aspect of the protein's function.