computational biology

Ask questions about projects relating to: biology, biochemistry, genomics, microbiology, molecular biology, pharmacology/toxicology, zoology, human behavior, archeology, anthropology, political science, sociology, geology, environmental science, oceanography, seismology, weather, or atmosphere.

Moderators: AmyCowen, kgudger, MadelineB, Moderators

Locked
deleted-133540
Posts: 6
Joined: Tue Apr 16, 2013 9:56 am
Occupation: Student,College
Project Question: Computational studies on microRNA cancer gene network
Project Due Date: 30-4-2013
Project Status: I am conducting my experiment

computational biology

Post by deleted-133540 »

How to find hubs in a network?
deleted-116311
Former Expert
Posts: 26
Joined: Mon Nov 19, 2012 4:38 pm
Occupation: Graduate student
Project Question: Science Fairs are Awesome!
Project Due Date: n/a
Project Status: Not applicable

Re: computational biology

Post by deleted-116311 »

Hi PoojaBhat,

I found a free review of biological network analysis:

http://genesdev.cshlp.org/content/21/9/ ... l.pdf+html

I hope that it helps.

Cheers,
Emily
deleted-133540
Posts: 6
Joined: Tue Apr 16, 2013 9:56 am
Occupation: Student,College
Project Question: Computational studies on microRNA cancer gene network
Project Due Date: 30-4-2013
Project Status: I am conducting my experiment

Re: computational biology

Post by deleted-133540 »

Thank You so much!
deleted-133540
Posts: 6
Joined: Tue Apr 16, 2013 9:56 am
Occupation: Student,College
Project Question: Computational studies on microRNA cancer gene network
Project Due Date: 30-4-2013
Project Status: I am conducting my experiment

Re: computational biology

Post by deleted-133540 »

Can you give me some project ideas which makes use of miRNA ids and their target genes for carcinoma?
It would be better if I can blend Computer science and Biological data.I want to extend the project and attach to the main project,so it must be related.
deleted-133540
Posts: 6
Joined: Tue Apr 16, 2013 9:56 am
Occupation: Student,College
Project Question: Computational studies on microRNA cancer gene network
Project Due Date: 30-4-2013
Project Status: I am conducting my experiment

Bioinformatics

Post by deleted-133540 »

How to find hubs in a network using cytoscape software?
SciB
Expert
Posts: 2071
Joined: Fri Feb 01, 2013 7:00 am
Occupation: Retired molecular biologist, university researcher and teacher
Project Question: I wish to join Scibuddies to be able to help students achieve the best science project possible and to understand the science behind it.
Project Due Date: n/a
Project Status: Not applicable

Re: computational biology

Post by SciB »

Hi PoojaBhat,

You have an ambitious and exciting project. As you know, cancer is a multifactorial disease and one miRNA can reduce expression of many genes--not just those directly related to tumor growth, angiogenesis, metastasis, drug resistance, etc.

I don't understand exactly what it is you are trying to do, but here's a good paper in which the authors created dbases for miRNA profiles from healthy vs malignant tissue and attempted to create networks. Maybe you already have seen it, but the references in that paper could give you some ideas about what else needs to be done.

Reprogramming of miRNA networks in cancer and leukemia [http://genome.cshlp.org/content/20/5/589.full]

If you have any specific questions, please let us know.

SciB
deleted-133540
Posts: 6
Joined: Tue Apr 16, 2013 9:56 am
Occupation: Student,College
Project Question: Computational studies on microRNA cancer gene network
Project Due Date: 30-4-2013
Project Status: I am conducting my experiment

Re: computational biology

Post by deleted-133540 »

Alright thank you :)
deleted-133540
Posts: 6
Joined: Tue Apr 16, 2013 9:56 am
Occupation: Student,College
Project Question: Computational studies on microRNA cancer gene network
Project Due Date: 30-4-2013
Project Status: I am conducting my experiment

Re: computational biology

Post by deleted-133540 »

Hello,
Could u please tell me few ideas about what can be done using software languages like php,sql,html,perl in bioinformatics?
Locked

Return to “Grades 9-12: Life, Earth, and Social Sciences”