Making Transcription Factors More Interesting

[deleted-181408]

I'm completing the project entitled "Taking Short Cuts: How Direct Reprogramming Can Transform One Type of Cell Straight into Another" and am simply looking for some help in how to make this topic more interesting for the judges of my project. Transcription factors are not everyone's favorite thing in the whole world, so I would like some help with ideas to make my project a bit more relatable to the average person.
I've chosen bone marrow as my target cell type, mainly because many people don't think about bone marrow. However, if someone could point me in the direction of some stories where direct reprogramming has gone successfully and majorly helped the patient, I would be very grateful.

Looking forward to feedback!

[sunmoonstars]

Hi keri,

I just found this video today and wanted to share it with you.

http://www.youtube.com/watch?v=Pe2wHiup ... e=youtu.be

Also, to answer your question, I did some searching with Google and found this information I think would help you:

http://www.cirm.ca.gov/our-progress/awa ... ll-therapy

http://www.ellisonfoundation.org/conten ... -potential

The direct reprogramming is pretty new. I am not aware that they are using the technique on human patients much... maybe in clinical trials.
http://clinicaltrials.gov/ct/search?ter ... mit=Search

Let me know if you have any more questions.
Tonya