Research on Schizophrenia now indicates that a deletion of a region on Chromosome 22 "22q11.2" is now the strongest link between Schizophrenia and even Autism.http://sfari.org/news-and-opinion/news/ ... izophrenia DiGeorge syndrome is the syndrome known for the syndrome caused by Chromosome 22 region "22q11.2" and causes several other effects in the body.
http://www.mayoclinic.org/diseases-cond ... n-20031464
Does having DiGeorge Syndrome automatically guarantee that you will have Schizophrenia?
Science Fair project on Schizophrenia
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Re: Science Fair project on Schizophrenia
Hi,
I do not belive that having DiGeorge Syndrome will mean the person also have schizophrenia. What the information means is that both conditions show some relation to the same portion of the chromosome. What it doesn't say specifically, but we understand to be true in general: 1- the chromosome location houses more than one gene, so the problem for the conditions could relate to different genes at the same location, 2- commonalities among patients (problem in specific locus), does not equal causation, meaning the genetic change there has not been proven to be the cause of the condition (it could be a coincidence, etc.), and 3- come disease states are caused by complex interactions among genes, and a problem with ONE gene is often not enough to cause a complex disease.
I hope this helps.
Tonya
I do not belive that having DiGeorge Syndrome will mean the person also have schizophrenia. What the information means is that both conditions show some relation to the same portion of the chromosome. What it doesn't say specifically, but we understand to be true in general: 1- the chromosome location houses more than one gene, so the problem for the conditions could relate to different genes at the same location, 2- commonalities among patients (problem in specific locus), does not equal causation, meaning the genetic change there has not been proven to be the cause of the condition (it could be a coincidence, etc.), and 3- come disease states are caused by complex interactions among genes, and a problem with ONE gene is often not enough to cause a complex disease.
I hope this helps.
Tonya

