CUT! How Does CRISPR Work?
- Model biotechnological mechanisms on a molecular level.
- Explain the molecular mechanism of CRISPR-Cas9 genome editing.
- Argue ethical implications of the CRISPR technology and its applications.
OverviewIn this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work independently (individually or in virtual groups) to brainstorm, storyboard, and film using the Brainstorming Worksheet, the Storyboard Template, and the Grading Rubric for guidance. The videos can then be shared online on a class drive or classroom sharing apps like Flipgrid. The Engage and Reflect sections can either be dropped entirely, done individually remotely, or be conducted over a video chat. NGSS AlignmentThis lesson helps students prepare for these Next Generation Science Standards Performance Expectations:
Materials![]()
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Grade Range
6th-12th
Group Size
1-3 students
Active Time
3 hours 30 minutes
Total Time
3 hours 30 minutes
Area of Science
Biotechnology
Genetics & Genomics
Genetic Engineering
Key Concepts
Gene editing, CRISPR
Credits
Svenja Lohner, PhD, Science Buddies
Learning Objectives
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