Solubility of Proteins
Summary
Areas of Science
Difficulty
Time Required
Long (2-4 weeks)
Prerequisites
Basic introduction to chemistry
Material Availability
A computer with Internet access is necessary for this project.
Cost
Very Low (under $20)
Safety
No issues
Credits
*Note:
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Abstract
Some proteins are soluble in aqueous solutions and some are not. Insoluble proteins can be a problem because the proteins can form large aggregates in solution which are difficult to purify, crystallize, and use in experiments. Compare the amino acid sequence and 3-D structures of some soluble and insoluble proteins (Berman, 2000). Is the structure polar or non-polar, and how might this affect solubility? How do detergents make an insoluble protein more soluble? Investigate how this technology is used to make cleaning products that are designed to break up the biochemical particulate matter that create stains on clothing and other surfaces. Are detergents or special enzymes involved?Bibliography
Berman, H.M., et. al., 2000. "The Protein Data Bank," Nucleic Acids Research, 28 pp. 235-242 (2000). [accessed 3/25/06] http://www.rcsb.org/pdb/Welcome.do.
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Cite This Page
General citation information is provided here. Be sure to check the formatting, including capitalization, for the method you are using and update your citation, as needed.MLA Style
Science Buddies Staff.
"Solubility of Proteins." Science Buddies,
28 July 2017,
https://www.sciencebuddies.org/science-fair-projects/project-ideas/BioChem_p018/biotechnology-techniques/solubility-of-proteins.
Accessed 16 May 2022.
APA Style
Science Buddies Staff.
(2017, July 28).
Solubility of Proteins.
Retrieved from
https://www.sciencebuddies.org/science-fair-projects/project-ideas/BioChem_p018/biotechnology-techniques/solubility-of-proteins
Last edit date: 2017-07-28
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