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Tracking COVID-19's Genomic and Clinical Evolution

Summary

Areas of Science
Difficulty
 
Time Required
Long (2-4 weeks)
Credits
Sandra Slutz, PhD, Science Buddies
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Abstract

Over time, viruses evolve. Their evolution is influenced by both neutral drift, the natural mutation rate of the virus, and selective pressure from the hosts' immune systems. Scientists study a virus's genomic evolution—the changes at the nucleotide and amino acid level—to better understand how the virus is spreading and the clinical implications. You can use public databases and tools to do the same type of tracking and analysis of COVID-19 that scientists around the world do.

SARS-CoV-2, the virus that causes the disease COVID-19, has been sequenced often from patients around the world. By comparing sequences from different patients, at the amino acid level, you can see whether there are any changes. If you find a change, there are many follow-up questions to ask, such as:

Here are some tips to help you start your scientific exploration:

icon scientific method

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Cite This Page

General citation information is provided here. Be sure to check the formatting, including capitalization, for the method you are using and update your citation, as needed.

MLA Style

Slutz, Sandra. "Tracking COVID-19's Genomic and Clinical Evolution." Science Buddies, 10 Nov. 2020, https://www.sciencebuddies.org/science-fair-projects/project-ideas/Genom_p026/genetics-genomics/COVID-19-mutations-clinical. Accessed 3 Oct. 2022.

APA Style

Slutz, S. (2020, November 10). Tracking COVID-19's Genomic and Clinical Evolution. Retrieved from https://www.sciencebuddies.org/science-fair-projects/project-ideas/Genom_p026/genetics-genomics/COVID-19-mutations-clinical


Last edit date: 2020-11-10
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