Antibiotic Resistance *
|Time Required||Long (2-4 weeks)|
|Prerequisites||This project requires access to bacteria and antibiotics in a laboratory setting. A basic knowledge of how to work with bacteria is needed to complete this science fair project. Consult the Microbiology Techniques and Troubleshooting guide for information on how to conduct microbiology experiments.|
|Material Availability||Specialty items, like bacteria and the media to grow them on, can be ordered from online vendors such as Carolina Biological Supply Company.|
|Cost||High ($100 - $150)|
|Safety||Requires adult supervision in a laboratory setting. Use sterile technique. Read the Microorganisms Safety Guide before starting any experiments. SRC approval may be necessary.|
AbstractAntibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different bacterial strains than others. Compare the action of different antibiotics on different strains of bacteria. Which type of antibiotic works the best against each strain? Which ones are the most cosmopolitan, and work on the most different strains of bacteria? Can you use genomic techniques and bioinformatics to predict which antibiotics will work best on each bacterial species or strain? (NCBI, 2006; Brown, 2002)
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Last edit date: 2018-05-05
- Brown, J. (2002). What the Heck is Antibiotic Resistance? Retrieved May 1, 2006, from the University of Kansas, Dept. of Molecular Biosciences website: http://people.ku.edu/~igmdoc/resistance.htm
- National Center for Biotechnology Information. (2006). Retrieved May 1, 2006, from https://www.ncbi.nlm.nih.gov/
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