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March 22, 2012
Antidepressants can play a key role in alleviating painful conditions like osteoarthritis and may result in fewer side effects than traditionally prescribed drug regimes, such as anti-inflammatories and opioids. That's the key finding of an analysis of the latest clinical evidence on duloxetine, a well-established antidepressant that has received FDA approval for use with chronic musculoskeletal pain, including osteoarthritis.
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March 11, 2012
An antidepressant combined with a drug derived from vitamin A could be used to treat a common adult form of leukemia, according to laboratory research led by a team at the Institute of Cancer Research.
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May 22, 2012
Researchers at Beth Israel Deaconess Medical Center, in Boston, and the Massachusetts Institute of Technology in Cambridge, have found that critically ill patients were more likely to die if they were taking the most commonly prescribed antidepressants when they were admitted to the intensive care unit (ICU).
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March 21, 2012
Use of selective serotonin re-uptake inhibitor antidepressants during pregnancy appears to be linked with increased risk of pregnancy induced high blood pressure (hypertension), but a causal link has not been established.
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February 8, 2012
Patients taking antidepressants up to three years prior to undergoing a total hip replacement (THR) were more likely to report greater pain before and after surgery and less satisfaction with their procedure, according to new research presented today at the 2012 Annual Meeting of the American Academy of Orthopedic Surgeons (AAOS).
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April 18, 2012
Scientists are reporting development and successful testing in laboratory mice of a substance that shows promise for becoming the first antidote for cocaine toxicity in humans. According to a report in ACS' journal Molecular Pharmaceutics, the new so-called "passive vaccine" reversed the motor impairment, seizures and other dangerous symptoms of a cocaine overdose, which claims thousands of lives each year among users of the illicit drug.
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January 4, 2012
Melanoma risk was 60 percent higher among those not taking antiestrogen therapy. Researcher cautions against widespread antiestrogen supplementation use. Study included 7,360 women with breast cancer.
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May 15, 2012
Pre-birth exposure to the anti-HIV drug tenofovir does not adversely affect pregnancy outcomes and does not increase birth defects, growth abnormalities, or kidney problems in infants born to African women who are HIV positive, supporting the use of this drug during pregnancy, according to a study by a team of international researchers published in this week's PLoS Medicine.
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May 1, 2012
Infants born to women who used the anti-HIV drug tenofovir as part of an anti-HIV drug regimen during pregnancy do not weigh less at birth and are not of shorter length than infants born to women who used anti-HIV drug regimens that do not include tenofovir during pregnancy, according to findings from a National Institutes of Health network study. However, at 1 year of age, children born to the tenofovir-treated mothers were slightly shorter and had slightly smaller head circumference.
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January 20, 2012
Shortages of key drugs used to fight infections represent a public health emergency and can put patients at risk, according to a review published in Clinical Infectious Diseases and available online. Frequent anti-infective shortages can substantially alter clinical care and may lead to worse outcomes for patients, particularly as the development of new anti-infectives has slowed and the prevalence of multidrug-resistant pathogens is increasing.
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