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April 10, 2012
Alzheimer's disease (AD) is now the sixth leading cause of death among Americans. There is currently no treatment that alters the course of this disease. However, an increasing amount of evidence suggests that changes in the way the body handles iron and other metals like copper and zinc may start years before the onset of AD symptoms. A new study shows that reducing iron levels in blood plasma may protect the brain from changes related to AD.
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May 29, 2012
A specific antioxidant supplement may be an effective therapy for some features of autism, according to a pilot trial from the Stanford University School of Medicine and Lucile Packard Children's Hospital that involved 31 children with the disorder.
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March 25, 2012
Researchers have found that the antiplatelet drug abciximab significantly decreased damage to the heart muscle in patients with ST-segment-elevation myocardial infarction, the most severe type of heart attack. Results of INFUSE-AMI trial were presented today at the ACC's 61st Annual Scientific Session and published simultaneously in the March 25th online issue of the Journal of the American Medical Association. Researchers also found that clot aspiration did not significantly reduce the damage…
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January 9, 2014
In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia, according to a study published in the Journal of Clinical Investigation. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.
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April 4, 2012
Low doses of a commonly used atypical antipsychotic drug improved survival in a mouse model of anorexia nervosa, University of Chicago researchers report this month. The result offers promise for a common and occasionally fatal eating disorder that currently lacks approved drugs for treatment.
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May 24, 2012
An anti-psychotic drug used to treat schizophrenia appears to get rid of cancer stem cells by helping them differentiate into less threatening cell types. The discovery reported in the Cell Press journal Cell on May 24 comes after researchers screened hundreds of compounds in search of those that would selectively inhibit human cancer stem cells, and it may lead rather swiftly to a clinical trial.
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May 28, 2012
While immediate post-exposure treatment for suspected HIV is critical, pre-exposure preventive treatment is a newer method that may be effective for people in high-risk groups, states a review of evidence published in CMAJ (Canadian Medical Association Journal).
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December 4, 2023
The U.S. Dept. of Education has initiated an investigation into Harvard University in response to allegations of anti-semitism on campus according to NBC News. The investigation follows a complaint asserting that Harvard failed to address incidents of harassment against Jewish and Israeli students. Harvard President Claudine Gay acknowledged the issue in a Nov. 9 letter,...
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January 3, 2012
A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The findings might offer a new therapy for this malignancy, which kills an estimated 549,000 people worldwide annually. The study focused on miR-221, which is consistently present at abnormally high levels in human liver cancer. The treatment significantly prolonged survival in an animal model and promoted the activity of important tumor-suppressor genes.
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February 27, 2012
Antisense oligonucleotides -- short segments of genetic material designed to target specific areas of a gene or chromosome -- that activated an enzyme to "chew up" toxic RNA could point the way to a treatment for a degenerative muscle disease called myotonic dystrophy, said researchers from Baylor College of Medicine and Isis Pharmaceuticals Inc., in a report in the journal Proceedings of the National Academy of Sciences.
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