Second Grade, Biotechnology Science Experiments (35 results)

Have you ever looked in the kitchen cupboard and found a container of tiny white grains, but you were not sure if they were sugar or salt? They look very similar. How could you tell them apart? Well, you know that sugar and salt taste very different. Taste is actually called a property, and properties are used to describe and identify different materials. Properties can also be used to physically separate things. In this science project, you will use different properties to create a way to… Read more

Your liver is important for cleaning up any potentially dangerous substances you consume. But how does it do it?—With a little help from some complex chemistry. Within your liver, as within every tissue in the body, many chemical reactions occur. Often these reactions require "help" to happen at a faster speed, and this can be supplied by enzymes—tiny types of proteins. The liver uses specialized enzymes to help it break down toxic substances and make them safer for the… Read more

Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change the sequence of the DNA. Will the same enzymes still cut the new DNA sequence? Read more

In order to study individual biochemical compounds like proteins, DNA, or RNA, biochemists need to know how to purify these components from a complex mixture. This is especially important for biotechnology and pharmaceutical industries, which sell purified biochemicals as reagents or drugs to consumers. Do an experiment to purify DNA, RNA, or protein from a complex mixture (for purifying DNA, see the Science Buddies project Extracting Onion DNA). The source of the material can be a cell… Read more

Some proteins are soluble in aqueous solutions and some are not. Insoluble proteins can be a problem because the proteins can form large aggregates in solution which are difficult to purify, crystallize, and use in experiments. Compare the amino acid sequence and 3-D structures of some soluble and insoluble proteins (Berman, 2000). Is the structure polar or non-polar, and how might this affect solubility? How do detergents make an insoluble protein more soluble? Investigate how this… Read more