High School, Biotechnology Projects, Lessons, Activities (27 results)

Yogurt, biofuel, biodegradable plastics, and antibiotics are all examples of products based on biotechnology research and manufacturing techniques. What else will we be able to create as we use biotechnology in new ways?

Do-It-Yourself DNA

STEM Activity

255 reviews

Have you ever wondered how scientists get a sample of DNA from a plant, animal, or other organism? All living organisms have DNA. DNA, which is short for deoxyribonucleic acid, is the blueprint for almost everything that happens inside the cells of an organism — overall, it tells the organism how to develop and function. DNA is so important that it can be found in nearly every cell of a living organism. In this activity, you will make your own DNA extraction kit from household… Read more

Genetically Modified Organisms: Create Glowing Bacteria!

Science Fair Project Idea

Scientific Method

Have you ever heard or read about GMO? GMO stands for genetically modified organisms. Scientists can deliberately modify the DNA of organisms, such as bacteria or plants, to change their properties for a specific purpose. For example, crops can be modified to become more drought- or pest-resistant. Genetic engineering is a very powerful tool in biotechnology that has already found many different applications in agriculture, medicine, and industry. In this project, you will engineer a… Read more

Oobleck: A Recipe for a Mesmerizing Mixture

STEM Activity

163 reviews

Have you ever wondered what whipped cream, jelly, and milk have in common? Aside from all being tasty, they are also all made up of tiny particles that are dispersed, or distributed, in water. This type of mixture is called a heterogeneous mixture. Some of these have very interesting physical properties, such as acting like a solid and a liquid at the same time! In this activity, you will get to create Oobleck, a mixture that is made using cornstarch and water, and then explore these… Read more

Enzyme-Catalyzed Reactions— What Affects Their Rates?

Science Fair Project Idea

Scientific Method

Enzymes speed up chemical reactions by factors of at least a million. Now that's acceleration! This project investigates how temperature affects how fast these enzymatic reactions occur. Read more

Forensic Science: Building Your Own Tool for Identifying DNA

Science Fair Project Idea

Scientific Method

When biologists want to separate different pieces of DNA, RNA, or proteins they use a technique called gel electrophoresis. In this science project you'll build a gel electrophoresis chamber and use it to discover how many components are in different colors of food coloring dye. Read more

Exploring DNA Damage: What Effect Do Ultraviolet Rays Have on Yeast Colony Growth?

Science Fair Project Idea

Scientific Method

Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more

CUT! How Does CRISPR Work?

Lesson Plan Grade: 6th-12th

6 reviews

In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more

NGSS Performance Expectations:

MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.

DNA Fingerprinting

Science Fair Project Idea

Scientific Method

Are you interested in the technical and ethical aspects of genetic screening, forensic science, and DNA fingerprinting? Scientists use different forms of a gene, called alleles, to differentiate between two fingerprints. One such sequence used in human DNA fingerprinting is the Alu repeat (a 300 base pair repetitive sequence of DNA) on chromosome 16. During evolutionary time, up to 1 million copies of the Alu repeat have become randomly inserted throughout the human genome. Within a specific… Read more

CRISPR Gene Editing of Escherichia coli

Science Fair Project Idea

Scientific Method

Many scientists are currently very excited about CRISPR, as it has the potential to revolutionize gene editing. But what exactly is CRISPR and what does it do? CRISPR is a novel tool in gene editing that allows the modification of genetic DNA at specific target sites in many different organisms. Researchers have high hopes that this technology can, one day, cure genetic diseases, as mutated DNA sequences can easily be corrected. In this project, you will use CRISPR to mutate a DNA sequence… Read more

Genetically Engineer Yeast to be Fluorescent

Science Fair Project Idea

Scientific Method

Can you imagine a glowing loaf of bread? You might not be able to make the whole loaf glow, but you can get baker's yeast to fluoresce! The way to do this is to modify the genetic information of the yeast organism. The technology that is used to do this is called genetic engineering. With genetic engineering, you can insert a fluorescent protein gene from a jellyfish into yeast cells, so they start glowing under blue light! Do this project to see for yourself! Read more

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