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Middle School, Biotechnology Projects, Lessons, Activities (18 results)

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Science Fair Project Idea
Scientific Method
What color is grape soda? If you pour it into a clear glass you can easily see it is purple, but that is usually not its natural color. Manufacturers add red and blue dye to the soda. The dyes mix together and you get purple soda. What if you wanted to un-mix the dyes, could you? Yes! In a chemistry laboratory, using a technique called column chromatography, you could separate the two dyes again. But what about at home, can you use low-tech supplies to do the same thing? In this science project… Read more
Science Fair Project Idea
Scientific Method
Can you imagine a glowing loaf of bread? You might not be able to make the whole loaf glow, but you can get baker's yeast to fluoresce! The way to do this is to modify the genetic information of the yeast organism. The technology that is used to do this is called genetic engineering. With genetic engineering, you can insert a fluorescent protein gene from a jellyfish into yeast cells, so they start glowing under blue light! Do this project to see for yourself! Read more
STEM Activity
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Did you know that you can change the genetic code of an organism? This technology is called gene editing or genetic engineering. Using gene editing tools, researchers can delete or modify existing genes in an organism, or even add new ones! With this ability, they can alter the way an organism—such as a bacteria, a plant, or an animal—looks or functions. For example, crops can be modified to become more drought-resistant, or bacteria can be engineered to produce medicine such as… Read more
Science Fair Project Idea
Scientific Method
Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change the sequence of the DNA. Will the same enzymes still cut the new DNA sequence? Read more
Science Fair Project Idea
Scientific Method
Have you ever looked in the kitchen cupboard and found a container of tiny white grains, but you were not sure if they were sugar or salt? They look very similar. How could you tell them apart? Well, you know that sugar and salt taste very different. Taste is actually called a property, and properties are used to describe and identify different materials. Properties can also be used to physically separate things. In this science project, you will use different properties to create a way to… Read more
Lesson Plan Grade: 6th-12th
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In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more
NGSS Performance Expectations:
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
Lesson Plan Grade: 6th-8th
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Using the context of apples, students will apply their knowledge of heredity and genetics to distinguish between sexual and asexual reproduction as they explain how new varieties of apples are developed and then propagated to meet consumer demand for a tasty, uniform, consistent product. Read more
NGSS Performance Expectations:
  • MS-LS4-4. Construct an explanation based on evidence that describes how genetic variations of traits in a population increase some individuals' probability of surviving and reproducing in a specific environment.
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
Lesson Plan Grade: 6th-8th
Students explore adaptations by researching how animals, plants, and bacteria change based on their environment. They grow bacterial colonies in various environments and hypothesize how each environment will affect the cell culture size and color. After a day of pre-growth, the culture is spun down in a centrifuge and the cell pellet is analyzed. Finally, students research bacteria adaptations that allow them to survive in extreme environments then brainstorm how the… Read more
NGSS Performance Expectations:
  • MS-LS1-5. Construct a scientific explanation based on evidence for how environmental and genetic factors influence the growth of organisms.
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