Biotechnology Science Experiments (Page 3)

Column Chromatography: Can you Separate the Dyes in Grape Soda Using Space Sand™?

Science Fair Project Idea

Scientific Method

What color is grape soda? If you pour it into a clear glass you can easily see it is purple, but that is usually not its natural color. Manufacturers add red and blue dye to the soda. The dyes mix together and you get purple soda. What if you wanted to un-mix the dyes, could you? Yes! In a chemistry laboratory, using a technique called column chromatography, you could separate the two dyes again. But what about at home, can you use low-tech supplies to do the same thing? In this science project… Read more

Create a Painting with Genetically Modified Bacteria

STEM Activity

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Did you know that you can change the genetic code of an organism? This technology is called gene editing or genetic engineering. Using gene editing tools, researchers can delete or modify existing genes in an organism, or even add new ones! With this ability, they can alter the way an organism—such as a bacteria, a plant, or an animal—looks or functions. For example, crops can be modified to become more drought-resistant, or bacteria can be engineered to produce medicine such as… Read more

Expression Cloning

Science Fair Project Idea

Scientific Method

What is expression cloning and how is it used in the biotechnology industry? How are plasmids constructed for use in a bacterial expression system? You can investigate these questions and more using bacterial expression kits meant for high school classes. You will need a laboratory space equipped to grow bacteria and carry out simple molecular biology. A kit with plasmids and bacterial cells to transform are also needed. Here are two possibilities: BioBuilder What a Colorful World Kit … Read more

Protein Structure and Function

Science Fair Project Idea

Scientific Method

How a biological system functions is a consequence of the 3-D structures of biological macromolecules like proteins and protein complexes. Proteins can be categorized into different protein families based upon sequence, structure, and function. Typically, proteins in the same family have similar biochemical functions. You can investigate the structure of a protein by using protein databases (Entrez Protein, SwissProt, PDB) and 3-D computational models. You can compare the structures of… Read more

Separating Butter with a Salad Spinner Centrifuge

Science Fair Project Idea

Scientific Method

Imagine that you could make an important piece of laboratory equipment in your kitchen. With this science project idea, you can! You will create your own centrifuge out of a salad spinner and some putty. In science labs, centrifuges are used to separate different liquids and/or solids from each other. You can load your homemade centrifuge with samples and see how they separate. What do you think happens to melted butter in a centrifuge? Read more

A Magnetic Primer Designer

Science Fair Project Idea

Scientific Method

How do scientists "copy" DNA? They use a process called the Polymerase Chain Reaction, or PCR. The key to making this process work is having a short piece of DNA, called a primer, that will stick to the larger piece of DNA you want to copy, called a template. In this science project, you will test how the number of matches and mismatches in a primer will affect its ability to stick, or anneal, to the DNA template during PCR. Read more

No Whey! Milk Protein Content Doesn't Change...Or Does It?

Science Fair Project Idea

Scientific Method

Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more

Separating Glitter with a Homemade Centrifuge

Science Fair Project Idea

Scientific Method

It is fun to shake up a snow globe and watch the "snow" slowly fall. You can imagine that if the snow fell down very quickly it would be disappointing. But there are times when scientists in a laboratory want this to happen. Scientists use samples that have liquid mixed with small, solid pieces (like the inside of a snow globe), and they need all of the solid pieces in a clump, separated from the liquid. Instead of waiting for the pieces to slowly fall out of the liquid, scientists speed up… Read more

Separating Mixtures: Can You Design a Device to Do It?

Science Fair Project Idea

Scientific Method

Have you ever looked in the kitchen cupboard and found a container of tiny white grains, but you were not sure if they were sugar or salt? They look very similar. How could you tell them apart? Well, you know that sugar and salt taste very different. Taste is actually called a property, and properties are used to describe and identify different materials. Properties can also be used to physically separate things. In this science project, you will use different properties to create a way to… Read more

Catalytic RNA and Structure

Science Fair Project Idea

Scientific Method

Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD (http://bioweb.pasteur.fr/seqanal/interfaces/mfold-simple.html) to submit your sequence for an… Read more

Biotechnology Science Experiments (35 results)

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