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High School, Experiment in Microbiology Science Projects (23 results)

By studying tiny microorganisms, learn how biological processes work at the cellular level. Experiment with testing disinfectants, growing microorganisms on agar plates, or creating products that beneficial microbes help make.

An Aerobic Exercise: Yeast Metabolism with and without Aeration
Science Fair Project Idea
Scientific Method
This is a straightforward project on glucose metabolism in yeast. You will grow yeast under aerobic and anaerobic conditions and measure carbon dioxide output to assess metabolic efficiency. Read more
Antibiotic Resistance
Science Fair Project Idea
Scientific Method
Antibiotics work by destabilizing the metabolism or cellular structure of bacteria, preventing growth, and causing bacteria to die. Some strains of bacteria have mutated and found a way to resist the actions of antibiotics. These are called resistant strains because they resist the actions of available antibiotic treatments. There are many different types of antibiotics that are continually being developed to combat new strains of resistant bacteria. Some antibiotics work better on different… Read more
Biowarfare: Experiment with Viruses that Destroy Bacteria
Science Fair Project Idea
Scientific Method
Most people are not aware that the soil around them is a battle scene. The combatants are very small—bacteria on one side and bacteriophage on the other. The bacteriophage (or phage for short) try to pierce the outer coats of the bacteria and inject them with phage DNA. If successful, the DNA will take over the inner machinery of the bacterial cells and force them to make many copies of the phage. After the copies are made, the bacterial cells break apart, releasing new phage that start… Read more
Can Garlic Prevent Crown Gall?
Science Fair Project Idea
Scientific Method
Crown gall is a plant disease caused by the soil bacterium Agrobacterium tumefaciens. This project uses tomato plants to investigate whether garlic extract can prevent crown gall infection. Read more
Cinnamon Gum and Mouth Microbes
Science Fair Project Idea
Scientific Method
Did you know that a scientific study has shown that chewing Big Red Gum reduces mouth microbes? (ScienceDaily contributors, 2004) The cinnamon oil in the gum is a natural defense against mouth bacteria that cause tooth decay and bad breath. Conduct an experiment to compare products with cinnamon essence in gum, candy, toothpaste, and mouthwash to see if they can decrease mouth germs. Do a before and after swab of the mouth with a Q-tip. Which treatments work the best? Can you find another… Read more
Death Rays: What Duration of Ultraviolet Exposure Kills Bacteria?
Science Fair Project Idea
Scientific Method
Ultraviolet light can damage DNA molecules. If a cell's DNA repair mechanisms can't keep up with the damage, mutations are the result. As harmful mutations accumulate, the cell eventually dies. How much ultraviolet light is too much for a bacterial cell? Read more
Disinfectants
Science Fair Project Idea
Scientific Method
Disinfectants are products that kill harmful bacteria that inhabit surfaces. Disinfectants can be in household and personal cleaning products. Which products work best? Compare different household cleaning products, like bleach or Lysol, to see which ones kill the most bacteria. Compare different brands of antibacterial hand soap or dish soap to see which brand is the most effective. How do hand sanitizers work? Compare rub-on hand sanitizers to see if they work better than alcohol, or compare… Read more
Do Different Dilutions of Disinfectants Affect the Development of Bacterial Resistance?
Science Fair Project Idea
Scientific Method
This is a project that illustrates the process of natural selection in action. You'll need access to a laboratory for working with the bacterial cultures used in this project. Read more
Exploring DNA Damage: What Effect Do Ultraviolet Rays Have on Yeast Colony Growth?
Science Fair Project Idea
Scientific Method
Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more
Expression Cloning
Science Fair Project Idea
Scientific Method
What is expression cloning and how is it used in the biotechnology industry? How are plasmids constructed for use in a bacterial expression system? You can investigate these questions and more using bacterial expression kits meant for high school classes. You will need a laboratory space equipped to grow bacteria and carry out simple molecular biology. A kit with plasmids and bacterial cells to transform are also needed. Here are two possibilities: BioBuilder What a Colorful World Kit … Read more
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