Tenth Grade, Biotechnology Projects, Lessons, Activities (Page 2)

Genetically Engineer Yeast to be Fluorescent

Science Fair Project Idea

Scientific Method

Can you imagine a glowing loaf of bread? You might not be able to make the whole loaf glow, but you can get baker's yeast to fluoresce! The way to do this is to modify the genetic information of the yeast organism. The technology that is used to do this is called genetic engineering. With genetic engineering, you can insert a fluorescent protein gene from a jellyfish into yeast cells, so they start glowing under blue light! Do this project to see for yourself! Read more

Genetically Modified Foods

Science Fair Project Idea

Scientific Method

Genetically modified organisms (GMOs) are organisms whose DNA have been manipulated to give them new traits. In genetically modified (GM) food crops traits like resistance to drought or pesticide might be added, or the crop may have been made more nutritious, or the taste may be altered to give you something like the impossible burger. Are there GMOs in your favorite foods? Many countries have implemented or are in the process of implementing GMO labeling on foods, but with a little bit of… Read more

Making Milk Curdle with Pineapple Enzymes

Science Fair Project Idea

Scientific Method

Have you ever gone to pour yourself a cup of milk and all you get is milk clumps? What happened to the milk is called coagulation, which is the mechanism that occurs when proteins in the milk clump together. While you do not necessarily want this in your milk, without coagulation (or curdling), there would not be any cheese or yogurt, which is why it is a very important process in the food industry. But what makes milk curdle? In this science project you will use pineapple juice to curdle milk… Read more

Transforming Bacteria to Make Colored Pigments

Science Fair Project Idea

Scientific Method

Can bacteria be altered to produce life-saving insulin for diabetics? Or change color to indicate the presence of a harmful toxin? Yes, it can! Using biotechnology, scientists work daily on problems like these. It starts with selecting a gene you want bacteria to produce and creating a sequence of DNA that has that gene and a promoter that will help express it at the right time and at the right levels. The next hurdle is actually getting this engineered DNA into the bacteria and… Read more

Bacteria Transformation

Lesson Plan Grade: 9th-12th

Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.Engineering Connection Bacteria are the most common organisms modified by genetic engineers due to… Read more

NGSS Performance Expectations:

HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.

Bio-Engineering: Making and Testing Model Proteins

Lesson Plan Grade: 9th-12th

Students act as if they are biological engineers following the steps of the engineering design process to design and create protein models to replace the defective proteins in a child's body. Jumping off from a basic understanding of DNA and its transcription and translation processes, students learn about the many different proteins types and what happens if protein mutations occur. Then they focus on structural, transport and defense proteins during three challenges… Read more

NGSS Performance Expectations:

HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
HS-LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
HS-ETS1-3. Evaluate a solution to a complex real-world problem based on prioritized criteria and trade-offs that account for a range of constraints, including cost, safety, reliability, and aesthetics, as well as possible social, cultural, and environmental impacts.

Catalytic RNA and Structure

Science Fair Project Idea

Scientific Method

Some sequences of RNA can catalyze biochemical reactions, much like protein enzymes. These catalytic RNA sequences are called ribozymes. The function of a ribozyme depends upon the primary sequence of the RNA which folds into a 3-D structure. How do different ribozyme sequences fold? You can search for ribozyme sequences using Entrez BLAST (NCBI, 2006). Then you can use a program like MFOLD (http://bioweb.pasteur.fr/seqanal/interfaces/mfold-simple.html) to submit your sequence for an… Read more

Design 'Y'er Genes

Lesson Plan Grade: 9th-12th

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This lesson introduces students to the relationships between chromosomes, genes, and DNA molecules. Using the example of a strawberry, it also provides activities that clearly show how changes in the DNA of an organism, either naturally or artificially, can cause changes. Read more

NGSS Performance Expectations:

HS-LS3-3. Heredity: Inheritance and Variation of Traits
Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population.

No Whey! Milk Protein Content Doesn't Change...Or Does It?

Science Fair Project Idea

Scientific Method

Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more

Protein Fingerprinting

Science Fair Project Idea

Scientific Method

First came the Human Genome Project and now (drum roll please) the Human Proteome Project. Confused? Not surprising as the Human Proteome Project has not received the kind of press that the Human Genome Project did. Nonetheless it is a major, and potentially important, scientific undertaking. Just as the genome is the complete set of an organism's DNA, the proteome is all the proteins expressed in an organism. Why study the proteome? It is because proteins are the work horses of biological… Read more

Tenth Grade, Biotechnology Projects, Lessons, Activities (24 results)

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