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Tenth Grade, Genetics & Genomics Projects, Lessons, Activities (21 results)

What traits are heritable? How different is your DNA from a frog's, a mouse's or even your relative's? Can your genes tell doctors what is the right dose of a medicine for your body? These are the types of questions scientists are answering with genetics and genomics. By studying individual genes as well as genomes, the whole set of DNA belonging to an organism, scientists hope to get a more complete understanding of how our bodies work and develop better disease treatments.

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CUT! How Does CRISPR Work?
Lesson Plan Grade: 6th-12th
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6 reviews
In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more
NGSS Performance Expectations:
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
Drugs & Genetics: Why Do Some People Respond to Drugs Differently than Others?
Science Fair Project Idea
Scientific Method
In a survey conducted from 2007 to 2010, the U.S. Centers for Disease Control and Prevention reported that about 49% of people in the United States had taken at least one prescription drug during the past month, and about 22% of people had taken three or more prescription drugs. People are prescribed drugs all the time, but prescriptions can be dangerous because people can have different responses to drugs. These responses largely have to do with genetic mutations. Why are some genetic… Read more
A Sweet Sequence: The Cacao Genome
Science Fair Project Idea
Scientific Method
Can you imagine Valentine's Day or Halloween without chocolate? Well, if you're a chocolate lover brace yourself for the bad news. According to the United States Department of Agriculture (USDA), "Worldwide demand for cacao now exceeds production." If there isn't enough cacao, the major raw ingredient for chocolate, then the chocolate supply will dwindle. Hang on! Before you start rushing to the store to buy all the chocolate you can get your hands on, a solution is already in the works. In… Read more
Bioinformatics - The Perfect Marriage of Computer Science & Medicine
Science Fair Project Idea
Scientific Method
Find out the real explanation for why your parents are so weird! Here is a science project that lets you explore the internet to find out why your "DNA blueprint" is so important to health and disease. In this science project, you will use methods that bioinformatics and biotech scientists perform on a daily basis to decipher the human genome in their efforts to diagnose and treat genetic diseases. Read more
BLAST into the Past to Identify T. Rex's Closest Living Relative
Science Fair Project Idea
Scientific Method
Believe it or not, scientists were recently able to recover tissue from a 68-million-year-old Tyrannosaurus rex fossil! Not only were they able to purify non-mineralized tissue, but they also succeeded in obtaining partial sequence information for protein molecules in the T. rex tissue. In this genomics science fair project, you will use the T. rex's protein sequence to search sequence databases for the its closest living relatives. Read more
BLASTing Flu Viruses
Science Fair Project Idea
Scientific Method
Remember going to the doctor and getting vaccine shots? It is no fun getting poked with a needle, but fortunately, a vaccine helps our immune system to develop protection against a serious illness for years to come. But what about the flu vaccine? How come there is a new one every year? This science fair project will show you why. Read more
From Prokaryotes to Eukaryotes: Solving Problems Using Plasmids
Lesson Plan Grade: 9th-12th
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This lesson compares and contrasts prokaryotic and eukaryotic cells and examines the form and function of the plasmid found in prokaryotic cells. Students will then use these principles to simulate how a desirable gene can be isolated and inserted into a plasmid as one step in the process of creating a genetically modified organism (GMO). Read more
NGSS Performance Expectations:
  • HS-LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
The Importance of Making Sure a Drug's Aim Is True
Science Fair Project Idea
Scientific Method
Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter our cells, and this is how infection is prevented. However, this also means that the bound protein no longer functions in our cells. How might these drugs accidentally disrupt important biological processes in our bodies? What other proteins might these drugs bind to? In this science project,… Read more
The Tree of Life — I (basic)
Science Fair Project Idea
Scientific Method
Imagine that a biologist arrived at your big family reunion and had no idea who were sisters, cousins, aunts, uncles, etc., but tried to sort it out by how all of you look. Just based on how you look, would s/he be able to guess whether the kid standing next to you is your sister or your cousin? The biologist might be able to make some good guesses this way, but by using samples of your family's DNA, s/he could construct your whole family tree. In this project, you'll use a Web-based… Read more
Tracking COVID-19's Genomic and Clinical Evolution
Science Fair Project Idea
Scientific Method
Over time, viruses evolve. Their evolution is influenced by both neutral drift, the natural mutation rate of the virus, and selective pressure from the hosts' immune systems. Scientists study a virus's genomic evolution—the changes at the nucleotide and amino acid level—to better understand how the virus is spreading and the clinical implications. You can use public databases and tools to do the same type of tracking and analysis of COVID-19 that scientists around the world do. … Read more
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