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Genetics & Genomics Projects, Lessons, Activities (39 results)

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Lesson Plan Grade: 9th-12th
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This lesson introduces students to the relationships between chromosomes, genes, and DNA molecules. Using the example of a strawberry, it also provides activities that clearly show how changes in the DNA of an organism, either naturally or artificially, can cause changes. Read more
NGSS Performance Expectations:
  • HS-LS3-3. Heredity: Inheritance and Variation of Traits
    Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population.
Lesson Plan Grade: 9th-12th
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This lesson compares and contrasts prokaryotic and eukaryotic cells and examines the form and function of the plasmid found in prokaryotic cells. Students will then use these principles to simulate how a desirable gene can be isolated and inserted into a plasmid as one step in the process of creating a genetically modified organism (GMO). Read more
NGSS Performance Expectations:
  • HS-LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
Lesson Plan Grade: 6th-8th
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Explore genetic variation through the world of taste in this problem-solving lesson plan. Working both individually and collaboratively, students figure out what kind of tasters they are, what this means about their own genetics, and how genetic mutations can lead to functional differences. This activity provides a hands-on, personalized opportunity to learn about how genotypes and phenotypes align. Read more
NGSS Performance Expectations:
  • MS-LS3-1. Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
  • MS-LS3-2. Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation.
Science Fair Project Idea
Scientific Method
Native plants are important for both ecological and medicinal reasons. However, most native plants are not very well studied. One way to know more about these plants is to understand which other species of plants they are most closely related to. In this science project you will sequence part of the chloroplast genome from a native plant and use this information to determine its evolutionary relationship to other species of plants. If the plant you chose has not been sequenced before, you can… Read more
Science Fair Project Idea
Scientific Method
This is a project about the "molecular alphabet" of DNA. With just four "letters," it manages to keep track of the plan for an entire person, and keep a complete copy in nearly every cell. This project will help you start learning this new alphabet. Read more
STEM Activity
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Have you ever seen a boy who looked just like his father when he was younger? We can often tell that two people are related because they have several similar physical traits. This is because children receive half of their DNA (i.e., their genetic blueprints) from each parent. What about fingerprints – are they an inherited trait? Fingerprints are used to identify people because each person’s fingerprints are unique, but people can have similar fingerprint patterns. This… Read more
Lesson Plan Grade: 9th-12th
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Students will compare and contrast methods of selective plant breeding, describe the scientific process of creating a genetically modified plant, compare genetically modified soybean seeds to conventional soybean seeds, describe the impact weeds have on plant growth, and understand how a genetically modified seed can help farmers manage weeds. Read more
NGSS Performance Expectations:
  • HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
  • HS-LS3-1. Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring.
Lesson Plan Grade: 6th-12th
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We hear about COVID-19 variants all the time, but what is a virus variant, how do they come about, and why do they matter? Students will explore these question and more in this lesson plan. They will use SimPandemic, a free online tool, to model what COVID-19 outbreaks look like when communities are exposed to different COVID-19 variants and understand how genetic mutations in a virus can lead to functional changes. Read more
NGSS Performance Expectations:
  • MS-LS2-4. Construct an argument supported by empirical evidence that changes to physical or biological components of an ecosystem affect populations.
  • MS-LS3-1. Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
  • HS-LS3-2. Make and defend a claim based on evidence that inheritable genetic variations may result from (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.
Lesson Plan Grade: 6th-8th
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This lesson uses problem-solving and logical thinking to introduce students to phylogenetic trees. Students will create, organize, and structure data to explore patterns of heredity. Learning Objectives Students will: Explore how phylogenetic trees organize species based on shared characteristics. Discover both the power and the limitations of phylogenetic trees as a tool for making inferences about the evolutionary history of different species. Engage in authentic science practices… Read more
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