High School, Medical Biotechnology Projects, Lessons, Activities (23 results)
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Have you ever wondered where acne comes from and how you can treat it? One major cause of acne is the colonization and infection of clogged pores with bacteria. In this science project, you'll test different acne medications and treatments to determine their effectiveness at killing bacteria.
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Antioxidants have become very popular in the news lately for their potential health and anti-aging properties. Antioxidants work by preventing oxidation reactions that produce free-radicals which can cause harm to the body. Try testing different vitamins for antioxidant activity. How do vitamins A, B, C, and E compare? Do some vitamins have more antioxidant activity than others? What are some other sources of antioxidants? Try testing extracts from proposed sources of antioxidants like coffee,…
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STEM Activity
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Biologic manufacturing is a multi-step process for creating a biological product that can help reduce symptoms or treat a disease. Below is an image of an overview of the drug development process you will be modeling.
Figure 1. Overview of the basic steps of the biologic development process modeled in this activity.
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In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the…
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Lesson Plan
Grade: 9th-12th
Students become biomedical engineers and create model viruses for use in therapeutic applications, such as gene therapy. In constructing their models, students carefully plan for side effects and modify a virus that can be used to safely to deliver gene therapy. This process involves taking a "wild type" (or unmodified) virus so it can target a specific area of the body.Engineering Connection
Genetic engineering is the artificial manipulation, modification, and…
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NGSS Performance Expectations:
Scientists recently found that some small drugs can stop infection by the deadly Ebola virus in
its tracks. Lab researchers found that these drugs bind to a protein that the Ebola virus uses to enter
our cells, and this is how infection is prevented. However, this also means that the bound protein no
longer functions in our cells. How might these drugs accidentally disrupt important biological processes
in our bodies? What other proteins might these drugs bind to? In this science project,…
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Have you ever known someone who had a bad reaction to a prescription drug? Although pharmaceutical companies test new drugs on a large number of people to make sure the drug works the way it is supposed to, often a small percentage of people respond differently to the drug. A person's genetics plays a large role in determining his or her response to a given drug. Our genes are made up of hundreds to millions of nucleotides of DNA (deoxyribonucleic acid), the genetic code. If just a single…
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Lesson Plan
Grade: 9th-12th
Students act as if they are biological engineers following the steps of the engineering design process to design and create protein models to replace the defective proteins in a child's body. Jumping off from a basic understanding of DNA and its transcription and translation processes, students learn about the many different proteins types and what happens if protein mutations occur. Then they focus on structural, transport and defense proteins during three challenges…
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NGSS Performance Expectations:
Unlocking the three-dimensional structure of a protein is crucial to help scientists understand how it functions in our bodies and how it can cause devastating diseases if it becomes disrupted or interacts in the wrong way. However, figuring out the structure of a protein in three-dimensional space can be very challenging. Proteins are the functional units of our cells, and every protein is made up of a long chain of amino acids. Amino acids come in different shapes and sizes, and they have…
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Lesson Plan
Grade: 8th-12th
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In this lesson, students will do a series of activities to explore the role of antibodies in our immune system. They will also investigate how doctors use monoclonal antibodies as part of immunotherapy to treat diseases like cancer.
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