Twelfth Grade, Genetic Engineering Science Projects (3 results)

Genetic engineering, also called gene editing or genetic modification, is the process of altering an organism's DNA in order to change a trait. This can mean changing a single base pair, adding or deleting a single gene, or changing an even larger strand of DNA. Using genetic engineering, genes from one organism can be added to the genome of a completely different species. It is even possible to experiment with synthesizing and inserting novel genes in the hopes of creating new traits.

Many products and therapies have already been developed using genetic engineering. For example, crops with higher nutritional value, improved taste, or resistance to pests have been engineered by adding genes from one plant species into another. Similarly, expression of a human gene in yeast and bacteria allows pharmaceutical companies to produce insulin to treat diabetic patients. In 2020, scientists had their first successful human trial with CRISPR (a genetic engineering technique), to correct a mutant gene that causes sickle cell anemia, a painful and sometimes deadly blood disease.

There are many different genetic engineering techniques, including molecular cloning and CRISPR, and new techniques are being developed rapidly. Despite this variety, all genetic engineering projects involve carrying out four main steps:

  1. Identifying the trait to be introduced, eliminated, or otherwise modified.
  2. Determining what piece of DNA needs to be added or removed in order to get the desired trait modification.
  3. Making the physical modifications to the organism's DNA.
  4. Verifying that the trait has been modified as desired.

Learn more about genetic engineering, and even try your hand at it, with these resources.

Science Fair Project Idea
In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
Science Fair Project Idea
Can you imagine Valentine's Day or Halloween without chocolate? Well, if you're a chocolate lover brace yourself for the bad news. According to the United States Department of Agriculture (USDA), "Worldwide demand for cacao now exceeds production." If there isn't enough cacao, the major raw ingredient for chocolate, then the chocolate supply will dwindle. Hang on! Before you start rushing to the store to buy all the chocolate you can get your hands on, a solution is already in the works. In… Read more
Science Fair Project Idea
Can bacteria be altered to produce life-saving insulin for diabetics? Or change color to indicate the presence of a harmful toxin? Yes, it can! Using biotechnology, scientists work daily on problems like these. It starts with selecting a gene you want bacteria to produce and creating a sequence of DNA that has that gene and a promoter that will help express it at the right time and at the right levels. The next hurdle is actually getting this engineered DNA into the bacteria and… Read more
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