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Twelfth Grade, Biotechnology Projects, Lessons, Activities (19 results)

Yogurt, biofuel, biodegradable plastics, and antibiotics are all examples of products based on biotechnology research and manufacturing techniques. What else will we be able to create as we use biotechnology in new ways?

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Exploring DNA Damage: What Effect Do Ultraviolet Rays Have on Yeast Colony Growth?
Science Fair Project Idea
Scientific Method
Though the Sun provides heat and light, which are essential for life on Earth, ultraviolet (UV) rays in sunlight can cause damage to DNA. In this science fair project, you will experiment with a strain of yeast that is super-sensitive to UV light. This project will demonstrate the lethal effects of UV light when DNA damage is not repaired. Read more
CUT! How Does CRISPR Work?
Lesson Plan Grade: 6th-12th
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In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more
NGSS Performance Expectations:
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
DNA Fingerprinting
Science Fair Project Idea
Scientific Method
Are you interested in the technical and ethical aspects of genetic screening, forensic science, and DNA fingerprinting? Scientists use different forms of a gene, called alleles, to differentiate between two fingerprints. One such sequence used in human DNA fingerprinting is the Alu repeat (a 300 base pair repetitive sequence of DNA) on chromosome 16. During evolutionary time, up to 1 million copies of the Alu repeat have become randomly inserted throughout the human genome. Within a specific… Read more
CRISPR Gene Editing of Escherichia coli
Science Fair Project Idea
Scientific Method
Many scientists are currently very excited about CRISPR, as it has the potential to revolutionize gene editing. But what exactly is CRISPR and what does it do? CRISPR is a novel tool in gene editing that allows the modification of genetic DNA at specific target sites in many different organisms. Researchers have high hopes that this technology can, one day, cure genetic diseases, as mutated DNA sequences can easily be corrected. In this project, you will use CRISPR to mutate a DNA sequence… Read more
Genetically Modified Foods
Science Fair Project Idea
Scientific Method
Genetically modified organisms (GMOs) are organisms whose DNA have been manipulated to give them new traits. In genetically modified (GM) food crops traits like resistance to drought or pesticide might be added, or the crop may have been made more nutritious, or the taste may be altered to give you something like the impossible burger. Are there GMOs in your favorite foods? Many countries have implemented or are in the process of implementing GMO labeling on foods, but with a little bit of… Read more
Transforming Bacteria to Make Colored Pigments
Science Fair Project Idea
Scientific Method
Can bacteria be altered to produce life-saving insulin for diabetics? Or change color to indicate the presence of a harmful toxin? Yes, it can! Using biotechnology, scientists work daily on problems like these. It starts with selecting a gene you want bacteria to produce and creating a sequence of DNA that has that gene and a promoter that will help express it at the right time and at the right levels. The next hurdle is actually getting this engineered DNA into the bacteria and… Read more
Expression Cloning
Science Fair Project Idea
Scientific Method
What is expression cloning and how is it used in the biotechnology industry? How are plasmids constructed for use in a bacterial expression system? You can investigate these questions and more using bacterial expression kits meant for high school classes. You will need a laboratory space equipped to grow bacteria and carry out simple molecular biology. A kit with plasmids and bacterial cells to transform are also needed. Here are two possibilities: BioBuilder What a Colorful World Kit … Read more
Making Milk Curdle with Pineapple Enzymes
Science Fair Project Idea
Scientific Method
Have you ever gone to pour yourself a cup of milk and all you get is milk clumps? What happened to the milk is called coagulation, which is the mechanism that occurs when proteins in the milk clump together. While you do not necessarily want this in your milk, without coagulation (or curdling), there would not be any cheese or yogurt, which is why it is a very important process in the food industry. But what makes milk curdle? In this science project you will use pineapple juice to curdle milk… Read more
Design 'Y'er Genes
Lesson Plan Grade: 9th-12th
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This lesson introduces students to the relationships between chromosomes, genes, and DNA molecules. Using the example of a strawberry, it also provides activities that clearly show how changes in the DNA of an organism, either naturally or artificially, can cause changes. Read more
NGSS Performance Expectations:
  • HS-LS3-3. Heredity: Inheritance and Variation of Traits
    Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population.
No Whey! Milk Protein Content Doesn't Change...Or Does It?
Science Fair Project Idea
Scientific Method
Many people you know probably have an opinion about the kind of milk they like to drink—some like it thin and refreshing, others like it thick and rich. Milk can be bought with different fat concentrations, but other than that, it's all the same. Or is it? This science fair project raises a few interesting questions about the other contents in milk. Do all milk products have the same protein concentrations? Do cows produce different types of milk during different stages of lactation?… Read more
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