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Genetic Engineering Projects, Lessons, Activities (19 results)

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Science Fair Project Idea
Scientific Method
Can bacteria be altered to produce life-saving insulin for diabetics? Or change color to indicate the presence of a harmful toxin? Yes, it can! Using biotechnology, scientists work daily on problems like these. It starts with selecting a gene you want bacteria to produce and creating a sequence of DNA that has that gene and a promoter that will help express it at the right time and at the right levels. The next hurdle is actually getting this engineered DNA into the bacteria and… Read more
Science Fair Project Idea
Scientific Method
Can you imagine Valentine's Day or Halloween without chocolate? Well, if you're a chocolate lover brace yourself for the bad news. According to the United States Department of Agriculture (USDA), "Worldwide demand for cacao now exceeds production." If there isn't enough cacao, the major raw ingredient for chocolate, then the chocolate supply will dwindle. Hang on! Before you start rushing to the store to buy all the chocolate you can get your hands on, a solution is already in the works. In… Read more
Science Fair Project Idea
Scientific Method
What is expression cloning and how is it used in the biotechnology industry? How are plasmids constructed for use in a bacterial expression system? You can investigate these questions and more using bacterial expression kits meant for high school classes. You will need a laboratory space equipped to grow bacteria and carry out simple molecular biology. A kit with plasmids and bacterial cells to transform are also needed. Here are two possibilities: BioBuilder What a Colorful World Kit … Read more
Science Fair Project Idea
Scientific Method
In the first decade of the 21st century, scientists found ways to make one adult cell type turn into a completely different cell type. This has huge implications for the medical field, including being able to take some cells that a person could spare, such as skin cells or blood cells, and turn them into another cell type that might be much more important for that person to have, such as cells to make a new kidney. How are scientists able to accomplish this amazing feat of "reprogramming" the… Read more
Science Fair Project Idea
Scientific Method
Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change the sequence of the DNA. Will the same enzymes still cut the new DNA sequence? Read more
Lesson Plan Grade: 9th-12th
Students become biomedical engineers and create model viruses for use in therapeutic applications, such as gene therapy. In constructing their models, students carefully plan for side effects and modify a virus that can be used to safely to deliver gene therapy. This process involves taking a "wild type" (or unmodified) virus so it can target a specific area of the body.Engineering Connection Genetic engineering is the artificial manipulation, modification, and… Read more
NGSS Performance Expectations:
  • HS-ETS1-2. Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.
Science Fair Project Idea
Scientific Method
How would you secretly mark a bank robber during a robbery? What could you do to ensure that the ethically grown cotton you grew and shipped off for weaving and garment making was used to make the shipment of shirts you received weeks later? When we want to tag and track something, we often use a barcode. From grocery store foods to FedEx packages, barcodes are a way of tagging and identifying items. The fact that barcodes can be unique and are easy to read are key features. Not all things… Read more
Lesson Plan Grade: 9th-12th
Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.Engineering Connection Bacteria are the most common organisms modified by genetic engineers due to… Read more
NGSS Performance Expectations:
  • HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
Lesson Plan Grade: 6th-8th
Students explore adaptations by researching how animals, plants, and bacteria change based on their environment. They grow bacterial colonies in various environments and hypothesize how each environment will affect the cell culture size and color. After a day of pre-growth, the culture is spun down in a centrifuge and the cell pellet is analyzed. Finally, students research bacteria adaptations that allow them to survive in extreme environments then brainstorm how the… Read more
NGSS Performance Expectations:
  • MS-LS1-5. Construct a scientific explanation based on evidence for how environmental and genetic factors influence the growth of organisms.
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