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High School, Genetics & Genomics Projects, Lessons, Activities (26 results)

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Lesson Plan Grade: 6th-12th
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In this lesson plan, students will take a closer look at the most recent developments in gene editing. Specifically, they will learn about the CRISPR technology using various interactive simulations and other resources. Based on their gained knowledge, students will create a model of the CRISPR-Cas9 components and create a stop-motion animation video of the molecular mechanism of CRISPR-Cas9. Remote learning adaptation: This lesson plan can be conducted remotely. Students can work… Read more
NGSS Performance Expectations:
  • MS-LS4-5. Gather and synthesize information about technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • HS-LS1-1. Construct an explanation, based on evidence, for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
Lesson Plan Grade: 9th-12th
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This lesson introduces students to the relationships between chromosomes, genes, and DNA molecules. Using the example of a strawberry, it also provides activities that clearly show how changes in the DNA of an organism, either naturally or artificially, can cause changes. Read more
NGSS Performance Expectations:
  • HS-LS3-3. Heredity: Inheritance and Variation of Traits
    Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population.
Lesson Plan Grade: 9th-12th
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This lesson compares and contrasts prokaryotic and eukaryotic cells and examines the form and function of the plasmid found in prokaryotic cells. Students will then use these principles to simulate how a desirable gene can be isolated and inserted into a plasmid as one step in the process of creating a genetically modified organism (GMO). Read more
NGSS Performance Expectations:
  • HS-LS1-2. Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
Science Fair Project Idea
Scientific Method
Native plants are important for both ecological and medicinal reasons. However, most native plants are not very well studied. One way to know more about these plants is to understand which other species of plants they are most closely related to. In this science project you will sequence part of the chloroplast genome from a native plant and use this information to determine its evolutionary relationship to other species of plants. If the plant you chose has not been sequenced before, you can… Read more
Lesson Plan Grade: 9th-12th
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Students will compare and contrast methods of selective plant breeding, describe the scientific process of creating a genetically modified plant, compare genetically modified soybean seeds to conventional soybean seeds, describe the impact weeds have on plant growth, and understand how a genetically modified seed can help farmers manage weeds. Read more
NGSS Performance Expectations:
  • HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
  • HS-LS3-1. Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring.
Lesson Plan Grade: 6th-12th
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We hear about COVID-19 variants all the time, but what is a virus variant, how do they come about, and why do they matter? Students will explore these question and more in this lesson plan. They will use SimPandemic, a free online tool, to model what COVID-19 outbreaks look like when communities are exposed to different COVID-19 variants and understand how genetic mutations in a virus can lead to functional changes. Read more
NGSS Performance Expectations:
  • MS-LS2-4. Construct an argument supported by empirical evidence that changes to physical or biological components of an ecosystem affect populations.
  • MS-LS3-1. Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
  • HS-LS3-2. Make and defend a claim based on evidence that inheritable genetic variations may result from (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.
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